14 documents found, page 1 of 2
Characterization of potential intoxications with medicines in a regional setting
Nascimento, Tânia; Santos, Teresa; Rato, Fátima; De Sousa-Coelho, Ana LuísaThe Portuguese Poison Information Center (from Portuguese—CIAV) is a call center that offers medical assistance in case of possible intoxication with any kind of product, including medicines. This center´s main goal is to inform and guide the general public and health professionals. This work aimed to analyze and compare data corresponding to the telephone calls from the Algarve region (South of Portugal), rece...
Gla-rich protein, magnesium and phosphate associate with mitral and aortic valv...
Silva, Ana P.; Viegas, Carla S. B.; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; Rato, Fátima; Santos, Nélio; Faísca, Marília; Almeida, EdgarAccelerated and premature cardiovascular calcification is a hallmark of chronic kidney disease (CKD) patients. Valvular calcification (VC) is a critical indicator of cardiovascular disease and all-cause mortality in this population, lacking validated biomarkers for early diagnosis. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor recently associated with vascular calcification, pulse pressure,...
Gla-Rich protein, magnesium and phosphate associate with mitral and aortic valv...
Silva, Ana P.; Viegas, Carla; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; Rato, Fátima; Santos, Nélio; Faísca, Marília; de Almeida, EdgarAccelerated and premature cardiovascular calcification is a hallmark of chronic kidney disease (CKD) patients. Valvular calcification (VC) is a critical indicator of cardiovascular disease and all-cause mortality in this population, lacking validated biomarkers for early diagnosis. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor recently associated with vascular calcification, pulse pressure,...
Animais Venenosos em Território Português: Abordagem Clínica de Picadas e Morde...
Valdoleiros, Sofia R.; Gonçalves, Inês Correia; Silva, Carolina; Guerra, Diogo; Silva, Lino André; Martínez-Freiría, Fernando; Rato, FátimaThere are many native species of animals with the potential to cause severe disease in Portugal. Of the four clinically relevant snake species, the vipers (Vipera latastei and Vipera seoanei) are the most concerning. They can cause severe disease and require in-hospital management, monitoring and specific treatment, including the administration of anti-snake venom serum. The Malpolon monspessulanus and Macropro...
Venomous Animals in the Portuguese Territory: Clinical Management of Bites and ...
Valdoleiros, Sofia R.; Gonçalves, Inês Correia; Silva, Carolina; Guerra, Diogo; Silva, Lino André; Martínez-Freiría, Fernando; Rato, FátimaThere are many native species of animals with the potential to cause severe disease in Portugal. Of the four clinically relevant snake species, the vipers (Vipera latastei and Vipera seoanei) are the most concerning. They can cause severe disease and require in-hospital management, monitoring and specific treatment, including the administration of anti-snake venom serum. The Malpolon monspessulanus and Macropro...
FGF23-klotho axis as predictive factors of fractures in type 2 diabetics with e...
Ribeiro, Ana Luisa; Mendes, Filipa; Carias, Eduarda; Rato, Fátima; Santos, Nélio; Neves, Pedro Leão; Silva, Ana PaulaBackground: The aim of our study was to evaluate the relevance of FGF23-klotho axis in the predisposition for bone fractures in type 2 diabetic patients with early chronic kidney disease. Methods: In a prospective study we included 126 type 2 diabetic patients with CKD stages 2-3 (from 2010 to 2017). We used descriptive statistics, ANOVA and chi-square test. Our population was divided into two groups according ...
Gla-rich protein (GRP) as an early and novel marker of vascular calcification a...
Silva, Ana P.; Viegas, Carla; Mendes, Filipa; Macedo, Ana; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; Rato, Fátima; Santos, NélioVascular calcification (VC) is one of the strongest predictors of cardiovascular risk in chronic kidney disease (CKD) patients. New diagnostic/prognostic tools are required for early detection of VC allowing interventional strategies. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor, whose clinical utility is here highlighted. The present study explores, for the first time, correlations betwee...
Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disea...
Silva, Ana; Mendes, Filipa; Carias, Eduarda; Gonçalves, Rui; Fragoso, André; Dias, Carolina; Tavares, Nelson; Café, Hugo; Santos, Nélio; Rato, FátimaBackground: Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and...
Resistin as a predictor of cardiovascular hospital admissions and renal deterio...
Bonito, Bruno; Silva, Ana Paula; Rato, Fátima; Santos, Nélio; Neves, Pedro LeãoBackground: High resistin levels have been associated with cardiovascular disease (CVD). Cardiovascular hospitalizations are common, especially in diabetic and renal impaired patients. The purpose of this study is to determine the role of serum resistin as a predictor of cardiovascular hospitalizations in type 2 diabetic patients with mild to moderate chronic kidney disease (CKD). Methods: We conducted a prospe...
Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disea...
Silva, Ana Paula; Mendes, Filipa; Carias, Eduarda; Baptista Gonçalves, Rui; Fragoso, André; Dias, Carolina; Tavares, Nelson; Mendonça Café, HugoResearch over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as ma...