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Roadmap on nanomedicine for the central nervous system

Ciofani, Gianni; Campisi, Marco; Mattu, Clara; Kamm, Roger D.; Chiono, Valeria; Raynold, Aji Alex Moothedathu; Freitas, João S.; Redolfi Riva, Eugenio

In recent years, a great deal of effort has been undertaken with regards to treatment of pathologies at the level of the central nervous system (CNS). Here, the presence of the blood-brain barrier acts as an obstacle to the delivery of potentially effective drugs and makes accessibility to, and treatment of, the CNS one of the most significant challenges in medicine. In this Roadmap article, we present the stat...


Development of Cationic Nanosystems Based on Poly (Styrene-Alt-Maleic Anhydride...

Raynold, Aji Alex Moothedathu

Documentos apresentados no âmbito do reconhecimento de graus e diplomas estrangeiros; Polymeric nanosystems have been extensively investigated for delivering active agents in cancer therapy. Clinical efficacy of conventional active ingredients in cancer treatment can be significantly enhanced using nanocarriers. Nanocarriers can passively target the cancer cells by enhanced permeation and retention (EPR) effect...


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