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Seasonality of mortality under climate change: a multicountry projection study

Madaniyazi, L; Armstrong, B; Tobias, A; Mistry, MN; Bell, ML; Urban, A; Kyselý, J; Ryti, N; Cvijanovic, I; Ng, CFS; Roye, D; Vicedo-Cabrera, AM; Tong, S

Background: Climate change can directly impact temperature-related excess deaths and might subsequently change the seasonal variation in mortality. In this study, we aimed to provide a systematic and comprehensive assessment of potential future changes in the seasonal variation, or seasonality, of mortality across different climate zones. Methods: In this modelling study, we collected daily time series of mean ...


Temperature frequency and mortality: Assessing adaptation to local temperature

Wu, Y; Wen, B; Gasparrini, A; Armstrong, B; Sera, F; Lavigne, E; Li, S; Guo, Y; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM

Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...


Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Tempera...

Hundessa, S; Huang, W; Zhao, Q; Wu, Y; Wen, B; Alahmad, B; Armstrong, B; Gasparrini, A; Sera, F; Tong, S; Madureira, J; Kyselý, J; Schwartz, J

Background: The association between nonoptimal temperatures and cardiovascular mortality risk is recognized. However, a comprehensive global assessment of this burden is lacking. Objectives: The goal of this study was to assess global cardiovascular mortality burden attributable to nonoptimal temperatures and investigate spatiotemporal trends. Methods: Using daily cardiovascular deaths and temperature data from...


Comparison for the effects of different components of temperature variability o...

Wen, B; Wu, Y; Guo, Y; Gasparrini, A; Tong, S; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM; Zanobetti, A; Analitis, A; Zeka, A

Background: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. Objectives: We aimed to assess the association of intra-day TV and inter-day TV with all-cause, cardiovascular, and respiratory mortality. Methods: We collected data on total, cardiovascular, and respiratory mortality and meteorology from 758...


Joint effect of heat and air pollution on mortality in 620 cities of 36 countries

Stafoggia, M; Michelozzi, P; Schneider, A; Armstrong, B; Scortichini, M; Rai, M; Achilleos, S; Alahmad, B; Analitis, A; Åström, C; Bell, ML; Calleja, N

Background The epidemiological evidence on the interaction between heat and ambient air pollution on mortality is still inconsistent. Objectives To investigate the interaction between heat and ambient air pollution on daily mortality in a large dataset of 620 cities from 36 countries. Methods We used daily data on all-cause mortality, air temperature, particulate matter ≤ 10 μm (PM10), PM ≤ 2.5 μm (PM2.5), nitr...


Interactive effects of ambient fine particulate matter and ozone on daily morta...

Liu, C; Chen, R; Sera, F; Vicedo-Cabrera, AM; Guo, Y; Tong, S; Lavigne, E; Correa, PM; Ortega, NV; Achilleos, S; Roye, D; Jaakkola, JJ; Ryti, N

Objective To investigate potential interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at global level. Design Two stage time series analysis. Setting 372 cities across 19 countries and regions. Population Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease. Main outcome measure Daily mortality data during 1994-2020. Stratified analyses by...


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