5 documents found, page 1 of 1
A Novel Bioanalytical Method for the Determination of Opioids in Blood and Peri...
Ferreira, Elisa; Real, Francisco Corte; Melo, Teresa Pinho e; Margalho, CláudiaOpioids are the drugs most commonly detected in overdose deaths and the second most consumed worldwide. An analytical methodology has been optimized and fully validated for the determination of codeine, morphine, 6-acetylmorphine, 6-acetylcodeine, oxycodone, oxymorphone and fentanyl in whole blood and pericardial fluid. The internal standards used were codeine-d3, morphine-d3, 6-acetylmorphine-d3 and fentanyl-d...
Assessment of IrisPlex-based multiplex for eye and skin color prediction with a...
Dario, Paulo; Mouriño, Helena; Oliveira, Ana Rita; Lucas, Isabel; Ribeiro, Teresa; Porto, Maria João; Santos, Jorge Costa; Dias, Deodália"DNA phenotyping research is one of the most emergent areas of forensic genetics. Predictions of externally visible characteristics are possible through analysis of single nucleotide polymorphisms. These tools can provide police with “intelligence” in cases where there are no obvious suspects and unknown biological samples found at the crime scene do not result in any criminal DNA database hits. IrisPlex, an ey...
Suicides in the Centre of Portugal: seven years analysis
Dias, Daniel; Mendonça, M. Cristina; Real, Francisco Corte; Vieira, Duarte Nuno; Teixeira, Helena M.As one of the more specific and distinctive problems of human beings, suicide has been investigated with increasing attention all over the world. Several risk factors have been described as well as limitations arising from their study. The World Health Organization estimates that this scourge affects one million people annually, which corresponds to one death every 40 s worldwide. According to recent studies, P...
A validated procedure for detection and quantitation of salvinorin a in pericar...
Margalho, Cláudia; Gallardo, Eugenia; Castanheira, Alice; Vieira, Duarte Nuno; López-Rivadulla, Manuel; Real, Francisco CorteThe use of vitreous humor and pericardial fluid as alternative matrices to blood and plasma in the field of forensic toxicology is described to quantitate low levels of Salvinorin A using ethion as internal standard. The method was optimized and fully validated using international accepted guidelines. The developed methodology utilizes a solid phase extraction procedure coupled to gas chromatography mass spectr...
Analysis of paternal lineages in Brazilian and African populations
Carvalho, Mónica; Brito, Pedro; Lopes, Virgínia; Andrade, Lisa; Anjos, Maria João; Real, Francisco Corte; Gusmão, LeonorThe present-day Brazilian population is a consequence of the admixture of various peoples of very different origins, namely, Amerindians, Europeans and Africans. The proportion of each genetic contribution is known to be very heterogeneous throughout the country. The aim of the present study was to compare the male lineages present in two distinct Brazilian populations, as well as to evaluate the African contri...