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Targeting circulating labile heme as a defense strategy against malaria

Ramos, Susana; Jeney, Viktoria; Figueiredo, Ana; Paixão, Tiago; Sambo, Maria Rosário; Quinhentos, Vatúsia; Martins, Rui; Gouveia, Zélia

Severe presentations of malaria emerge as Plasmodium (P.) spp. parasites invade and lyse red blood cells (RBC), producing extracellular hemoglobin (HB), from which labile heme is released. Here, we tested whether scavenging of extracellular HB and/or labile heme, by haptoglobin (HP) and/or hemopexin (HPX), respectively, counter the pathogenesis of severe presentations of malaria. We found that circulating labil...


The influence of serious games in the promotion of healthy diet and physical ac...

Lamas, Susana; Rebelo, Sofia; Costa, Sofia da; Sousa, Helena; Zagalo, Nelson; Pinto, Elisabete

(1) Background: serious games seem to show promising strategies to promote treatment compliance and motivate behavior changes, and some studies have proven to contribute to the literature on serious games. (2) Methods: this systematic review aimed to analyze the effect of serious games in promoting healthy eating behaviors, effectively preventing childhood obesity, and improving physical activity in children. F...


The influence of serious games in the promotion of healthy diet and physical ac...

Lamas, Susana; Rebelo, Sofia; Costa, Sofia da; Sousa, Helena; Zagalo, Nelson; Pinto, Elisabete

(1) Background: serious games seem to show promising strategies to promote treatment compliance and motivate behavior changes, and some studies have proven to contribute to the literature on serious games. (2) Methods: this systematic review aimed to analyze the effect of serious games in promoting healthy eating behaviors, effectively preventing childhood obesity, and improving physical activity in children. F...


Controlo radiográfico de dispositivos médicos em neonatologia: revisão narrativa

Reis, Raquel; Rebelo, Sofia; Pereira, José Manuel

Introdução: A gestão clínica dos recém-nascidos nas unidades de cuidados intensivos neonatais implica a colocação de diversos dispositivos médicos invasivos que necessitam de controlo radiográfico. O principal objetivo deste trabalho consistiu em realizar uma revisão narrativa sobre as boas práticas a adotar na aquisição de imagens radiográficas, em unidades de cuidados intensivos neonatais, para o controlo de ...


Controlo radiográfico de dispositivos médicos em neonatologia

Reis, Raquel; Rebelo, Sofia; Pereira, José Manuel; Pereira, José Manuel

A gestão clínica dos recém-nascidos nas unidades de cuidados intensivos neonatais implica a colocação de diversos dispositivos médicos invasivos que necessitam de controlo radiográfico. O principal objetivo deste trabalho consistiu em realizar uma revisão narrativa sobre as boas práticas a adotar na aquisição de imagens radiográficas, em unidades de cuidados intensivos neonatais, para o controlo de dispositivos...


Radiographic control of medical devices in neonatology: a narrative review

Reis, Raquel; Rebelo, Sofia; Pereira, José Manuel

Introduction: During the stay of a newborn in the intensive unit, the clinical care management can involve the placement of invasive medical devices that need to be controlled by x-ray. The main goal of this work is to make a narrative review about the quality of imaging acquisition for radiographic confirmation of invasive medical devices in the neonatal intensive care units, according to the literature and th...


Gamification as an engagement tool in e-Learning websites

Rebelo, Sofia; Isaías, Pedro

Aim/Purpose As e-Learning becomes increasingly pervasive, students’ engagement in online settings emerges as a central challenge, as it is often more demanding to ensure in this context. The core importance of engagement for e-Learning, places a focus on various instruments and strategies that can be deployed to foster its enhancement. Background Gamification is often depicted as a significant instrument to dri...


Transversalidades: matemática e português nos primeiros anos

Rebelo, Sofia; Colaço, Susana

As narrativas infantis desempenham um papel fundamental no desenvolvimento de competências no domínio da Matemática do 1.ºCEB, nomeadamente quando se pretende trabalhar a transversalidade entre a Matemática e o Português. Nesta comunicação pretende-se apresentar uma parte do trabalho do estágio desenvolvido no âmbito do Mestrado em Educação Pré-escolar e Ensino do 1.ºCEB onde se procurou que a transversalidade ...


Gender norms in Portuguese college sudents' judgments in familial homicides: ba...

Saavedra, Luísa; Cameira, Miguel; Rebelo, Sofia; Sebastião, Cátia

The gender of the offender has been proved to be an important factor in judicial sentencing. In this study, we analyze the judgments of College students regarding perpetrators of familial homicides to evaluate the presence of these gender norms and biases in the larger society. The sample included 303 college students (54.8% female) enrolled in several social sciences and engineering courses. Participants were ...


Metabolic Adaptation to Tissue Iron Overload Confers Tolerance to Malaria

Gozzelino, Raffaella; Andrade, Bruno Bezerril; Larsen, Rasmus; Luz, Nívea Farias; Vanoaica, Liviu; Seixa, Elsa; Coutinho, Antonio

Texto completo: acesso restrito. p. 693–704; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-05-06T17:00:53Z No. of bitstreams: 1 Manoel Barral Netto.pdf: 1535112 bytes, checksum: 511e0bbfefaaf21eb5c649bab7871771 (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-10-21T16:43:41Z (GMT) No. of bitstreams: 1 Manoel Barral Netto.pdf: 1535112 bytes, checksum: 511e...

Date: 2014   |   Origin: Oasisbr

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