Parkinson’s Disease (PD) is a clinical diagnosis that relies on the presence of bradykinesia and rigidity and/or rest tremor. Whereas the striatal dopamine depletion explains the characteristic PD symptoms such as bradykinesia and rigidity, the mechanism of tremor generation is not completely established. Mounting evidence suggests that resting tremor is associated with increased activity in a distinct cerebell...
Background: The relationship between Parkinson's disease (PD) and cardiovascular and cerebrovascular disease is not yet well established. Recent data suggest an increased risk of myocardial infarction and stroke in PD patients. Therefore, we designed a study to assess surrogate markers of cardiovascular and cerebrovascular risk in PD. Methods: We conducted a case-control study comparing PD patients recruited fr...