Schwannomas are tumors originated from Schwann cells. Normally is located in the head, neck and limbs, but it can occur anywhere in the body where there are myelinated nerves. Renal involvement is rare, with few cases reported in the literature. The preoperative diagnosis is difficult, since it is based only on a specific clinical presentation and limited radiological resources. Although some MRI findings may r...
Recently, it has been observed an association between BPH and ED. It was reported that patients with ED treated with inhibitory phosphodiesterase type 5 (IPDE5) improves erection and LUTS. The pathophysiology of lower urinary tract symptoms (LUTS) is not completely known, so it is necessary that clinical and experimental studies are made to clarify the mechanisms involved in its origin. However, despite the kno...
Purpose: The aim of this study was to define if tadalafil causes detrusor muscle impairment and to observe the effect of combination of tadalafil with tamsulosin on the lower urinary tract of rats with bladder outlet obstruction (BOO) induced by chronic nitric oxide deficiency. Materials and Methods: Thirty-one male rats were randomized to following groups: 1 - control; 2 - L-Nitroarginine methyl ester (L-NAME)...
Recently, the focus of the origin of lower urinary tract symptoms (LUTS) has change from the prostate to the bladder. Regardless of the underlying mechanism associated with the origin of LUTS, alpha-blockers continue to be the most common medicine prescribed to treat LUTS due to benign prostatic obstruction (BPO). The newest class of drug introduced to treat LUTS/BPO is phosphodiesterase inhibitors (PDEi) and t...
The toothache plant (Spilanthes oleracea or Spilanthes acmella oleracea or simply Acmella oleracea) is a well-known herb in Northern Brazil, especially in Pará, where it is referred to as jambu. Though commonly used in the local cuisine in dishes such as tacacá and pato-no-tucupi, it is also widely used to prepare analgesic, antiinflammatory and antifungal medications. Extracts of this plant have recently becom...