7 documents found, page 1 of 1
Gene-Edited Human-Induced Pluripotent Stem Cell Lines to Elucidate DAND5 Functi...
Inácio, José M; Nunes, Mafalda M; Almeida, Micael; Cristo, Fernando; Anjos, Rui; A. Belo, JoséFunding: This work was supported by Fundação para a Ciência e a Tecnologia (PTDC/ BIMMED/3363/2014) and Scientific Employment Stimulus to J.M.I. (Norma Transitória 8189/2018), predoctoral fellowship to M.A. (FCT; 06890/2021/BD), post-doctoral fellowship to F.C. (DAI 2019/08/ SAICTPAC/0047/2015) and iNOVA4Health – UIDB/04462/2020 and UIDP/04462/2020, two programs financially supported by Fundação para a Ciência ...
Myocardial RNA Sequencing Reveals New Potential Therapeutic Targets in Heart Fa...
Inácio, José M.; Cristo, Fernando; Pinheiro, Miguel; Vasques-Nóvoa, Francisco; Saraiva, Francisca; Nunes, Mafalda M.; Rosas, Graça; Reis, AndreiaFunding Information: This work was supported by the Fundação para a Ciência e a Tecnologia (NETDIAMOND-SAICTPAC/0047/2015), Scientific Employment Stimulus to J.M.I. (Norma Transitória 8189/2018), post-doctoral fellowship to F.C. (DAI/2019/08/SAICTPAC/0047/2015), iNOVA4Health-UID/Multi/04462/2020 and LS4FUTURE Associated Laboratory (LA/P/0087/2020). Genome Medicine Lab is funded by FCT and COMPETE2020 (iBiMED: U...
A novel biallelic loss-of-function variant in DAND5 causes heterotaxy syndrome
Ganapathi, Mythily; Buchovecky, Christie M.; Cristo, Fernando; Ahimaz, Priyanka; Ruzal-Shapiro, Carrie; Wou, Karen; Inácio, José M.; Iglesias, AlejandroFunding J.A.B. acknowledges funding from iNOVA4Health-UID/Multi/04462/2013, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência through national funds and cofunded by Fundo Europeu de Desenvolvimento Regional (FEDER) under the PT2020 Partnership Agreement.; The majority of heterotaxy cases do not obtain a molecular diagnosis, although pathogenic variants in m...
DAND5 Inactivation Enhances Cardiac Differentiation in Mouse Embryonic Stem Cells
Inácio, José Manuel; von Gilsa Lopes, João; Silva, Ana Mafalda; Cristo, Fernando; Marques, Sara; Futschik, Matthias E.; A. Belo, JoséFunding: This work was supported by the Fundação para a Ciência e a Tecnologia (PTDC/BIM-MED/3363/2014) and Scientific Employment Stimulus to JI (Norma Transitória 8189/2018), predoctoral fellowship to JG (FCT; PD/BD/136919/2018) and postdoctoral fellowship to FC (DAI/ 2019/08/SAICTPAC/0047/2015), and iNOVA4Health-UID/Multi/04462/2013, a program financially supported by Fundação para a Ciência e a Tecnologia/Mi...
Generation of a gene-corrected human induced pluripotent stem cell line derived...
Inácio, José M.; Almeida, Micael; Cristo, Fernando; A. Belo, JoséThis work was supported by Fundação para a Ciência e a Tecnologia (PTDC/ BIM-MED/3363/2014) and iNOVA4Health -UID/Multi/04462/ 2013, a program financially supported by Fundação para a Ciência e Tecnologia/ Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement.; Human induced pluripotent stem cells (hiPSCs) from individual patient basis are conside...
Generation and characterization of a human iPS cell line from a patient-related...
Pars, Selin; Cristo, Fernando; Inácio, José M; Rosas, Graça; Carreira, Isabel Marques; Melo, Joana Barbosa; Mendes, Patrícia; Martins, Duarte SaraivaWe would like to thank the patient and their guardians for their generous donation of the urine sample used in this study. We also would like to thank Ana Jardim for technical support in karyotype analysis. This work was supported by Fundacao para a Ciencia e a Tecnologia (PTDC/BIM-MED/3363/2014). iNOVA4Health - UID/Multi/04462/2013, a program financially supported by Fundacao para a Ciencia e Tecnologia/Minist...
Generation of human iPSC line from a patient with laterality defects and associ...
Cristo, Fernando; Inácio, José M.; Rosas, Graça; Carreira, Isabel Marques; Melo, Joana Barbosa; de Almeida, Luís Pereira; Mendes, PatríciaWe would like to thank the patient and their guardians for their generous donation of the urine sample used in this study. We also would like to thank Ana Jardimfor technical support in karyotype analysis. This work was supported by Fundacao para a Ciencia e a Tecnologia (PTDC/BIM-MED/3363/2014). iNOVA4Health - UID/Multi/04462/2013, a program financially supported by Fundacao para a Ciencia e Tecnologia/Ministe...