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Evaluation of Sexual Dimorphism in the Efficacy and Safety of Simvastatin/Atorv...
Smiderle,Lisiane; Lima,Luciana O.; Hutz,Mara Helena; Sand,Cézar Roberto Van der; Van der Sand,Luiz Carlos; Ferreira,Maria Elvira WagnerBackground: Dyslipidemia is the primary risk factor for cardiovascular disease, and statins have been effective in controlling lipid levels. Sex differences in the pharmacokinetics and pharmacodynamics of statins contribute to interindividual variations in drug efficacy and toxicity. Objective: To evaluate the presence of sexual dimorphism in the efficacy and safety of simvastatin/atorvastatin treatment. Method...
Data: 2014
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Origem: Oasisbr