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Reversible Visual and Neurological Manifestations of Nonketotic Hyperglycemia: ...

Abreu, Carolina; Azevedo Ferreira, Marta; Palma Féria, Rita; Reis, Ana

Nonketotic hyperglycemia (NKH) has been associated with visual field and neurological alterations, typically reversible with glycemic control. A 54-year-old woman with hypertension and dyslipidemia presented in the emergency department with a 2-week history of headaches, left visual field photopsia and polydipsia and polyuria. Examination revealed homonymous left hemianopia, along with brief episodes of head an...

Date: 2025   |   Origin: SPMI Case Reports

Adrenal insufficiency due to post-surgical stress: case report

Reis, Ana; Nogueira, Joana

Introduction: Adrenal insufficiency is a clinical condition that may be due to multiple pathologies that affect the adrenal glands' synthesis and/or secretion of cortisol. The clinical presentation can vary from an adrenal crisis (acute adrenal insufficiency) to a gradual onset of non-specific symptoms (chronic adrenal insufficiency). In this article, we describe the case of a patient who developed symptoms of ...


Heterotrophic cultivation of Chlorella vulgaris yellow mutant on sidestreams: M...

Trovão, Mafalda; Barros, Ana; Machado, Adriana; Reis, Ana; Pedroso, Humberto; Espírito Santo, Gonçalo; Correia, Nádia; Costa, Monya; Ferreira, Sara

Microalgal protein is a promising feedstock to complement and/or replace other protein sources. Besides requiring less land and water usage, microalgae production is a more sustainable process, especially if industrial sidestreams are used as nutrient sources. Additionally, the heterotrophic cultivation of microalgae, such as Chlorella vulgaris, enables the achievement of much higher biomass productivity and lo...


Oxyfluorfen: a novel metabolic inhibitor to select microalgal chlorophyll-defic...

Trovão dos Santos, Mafalda; Cardoso, Lucas; Schüler, Lisa; Machado, Adriana; Santo, Gonçalo Espírito; Pedroso, Humberto; Reis, Ana; Barros, Ana

Nowadays, there is an increasing demand for novel feedstocks and alternative protein sources to meet global needs. Because of their rich nutritional profiles and high protein contents, microalgae-based food products and supplements are being developed. Nonetheless, these products present organoleptic characteristics such as taste, smell and colour that are often considered unpleasant by human and animal consume...


Perfectionism and emotion regulation in the study of suicidal ideation in portu...

Brás, Marta; Antunes, João; Reis, Ana; Carmo, Cláudia

Suicide is a serious public health problem worldwide, being the culmination of a process that normally begins with suicidal ideation. Therefore, it is important to assess suicidal ideation and know its risk factors. The association between perfectionism and suicidal ideation has been widely debated in the literature. However, knowledge about the role of emotion regulation in this relationship is scarce. The mai...


Isolation and selection of protein-rich mutants of chlorella vulgaris by fluore...

Trovão dos Santos, Mafalda; Schüler, Lisa; Pedroso, Humberto; Reis, Ana; Santo, Gonçalo Espírito; Barros, Ana; Correia, Nádia; Ribeiro, Joana

Microalgae are a promising feedstock with proven biostimulant activity that is enhanced by their biochemical components (e.g., amino acids and phytohormones), which turns them into an appealing feedstock to reduce the use of fertilisers in agriculture and improve crop productivity and resilience. Thus, this work aimed to isolate protein-rich microalgal mutants with increased biostimulant activity. Random mutage...


Multidose Drug Dispensing Systems: a market study

Reis, Ana; Alves, Sandra; Jesus, Ângelo; Calvo, María

Background: This study investigates the willing to pay for a Multidose Drug Dispensing System (MDD) in pharmacies. Objective: The main aim of this study is to determine whether MDD is perceived as important in society (users or not) and their willing to pay for it. OMS concluded that increasing interventions to improve adherence to therapy may have more impact on the population’s health than any improvement in ...


Integrated Use of Bioaccumulation, Genotoxic, and Haematological Endpoints to A...

Mieiro, Cláudia Leopoldina; Coelho, João; Reis, Ana; Castro, Diana; Figueira, Paula; Martinho, Filipe; Pardal, Miguel; Pereira, Eduarda; Pacheco, Mário

Biosorption successfully remediates saline water contaminated with legacy contaminants, but its effects on the health of marine organisms remain unclear. Therefore, our aim was to address this knowledge gap with data on the accumulation ability, as well as the cytogenetic and biochemical effects in turbot (Scophthalmus maximus). To this end, we exposed turbot for seven days to a mixture of remediated metals (Re...


From the first to the fourth critical period of COVID-19: what has changed in n...

Ribeiro, Olga; Cardoso, Maria Filomena; de Lima Trindade, Letícia; da Rocha, Carla Gomes; Teles, Paulo João Figueiredo Cabral; Pereira, Soraia

Background The COVID-19 pandemic reinforced the need to invest in nursing practice environments and health institutions were led to implement several changes. In this sense, this study aimed to analyze the impact of the changes that occurred in nursing practice environments between the first and fourth critical periods of the pandemic. Methods Quantitative, observational study, conducted in a University Hospita...


Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the ox...

Reis, Ana; Rocha, Sara; Dias, Irundika HK.; Costa, Raquel; Soares, Raquel; Sánchez-Quesada, José Luis; Perez, Antonio; Freitas, Victor de

The incidence of diabetes on the worldwide population has tripled in the past 5 decades. While drug-based therapies are valuable strategies to treat and ease the socio-economic burden of diabetes, nutritional strategies offer valuable alternatives to prevent and manage diabetes onset and contribute to the sustainability of health budgets. Whilst, intervention studies have shown that (poly)phenol-rich diets impr...


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