Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among hospitalized patients in Portugal. Material and methods: Retrospective study conducted in six public hospital centers in Portugal. All primary Clostridioides difficile inf...
In the last few decades there has been a widespread of the use of central neuraxial blockages (CNB) in obstetric patients. The complications from the CNB range from the bothersome to the crippling and life-threatening. Spinal epidural hematoma (SEH) is one of such severe complications. A 29-year-old pregnant woman at term, ASA II, was proposed for a caesarean section after inadequate progression of labour. Spin...
Despite elevated incidence and recurrence rates for Primary Spontaneous Pneumothorax (PSP), little is known about its etiology, and the genetics of idiopathic PSP remains unexplored. To identify genetic variants contributing to sporadic PSP risk, we conducted the first PSP genome-wide association study. Two replicate pools of 92 Portuguese PSP cases and of 129 age- and sex-matched controls were allelotyped in t...
Tetanus is a disease of safe and easy prevention, although it continues to be a frequent pathology, with variable incidence in different countries. Portugal occupies one of the top positions in European countries. The aim of this theoretic revision is a greater sensitivity to the prevention and diagnosis of the disease.; Tetanus is a disease of safe and easy prevention, although it continues to be a frequent pa...