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Spontaneous systolic blood pressure drop early after mechanical thrombectomy pr...

Carvalho Dias, Mariana; Gabriel, Denis; Saraiva, Marlene; Campos, Daniel; Requena, Manuel; García-Tornel, Álvaro; Muchada, Marian; Boned, Sandra

Introduction: Spontaneous blood pressure drop within the first 24 h has been reported following arterial recanalisation in ischaemic stroke patients. We aimed to assess if spontaneous blood pressure drop within the first hour after mechanical thrombectomy is a marker of early neurological recovery. Patients and methods: Retrospective observational single-centre study including ischaemic stroke patients treated ...


Association of a genetic variant in the ALOX5AP with higher risk of ischemic st...

Domingues-Montanarie, Sophie; Fernández-Cadenas, Israel; Rio-Espinola, Alberto del; Corbeto, Natalia; Krug, Tiago; Manso, Helena; Gouveia, Liliana

Background: Variants in the 5-lipoxygenase-activating protein (ALOX5AP) and phosphodiesterase 4D (PDE4D) genes have first been associated with ischemic stroke (IS) through whole-genome linkage screens. However, association studies obtained conflicting results. We aimed to investigate the contribution of selected single nucleotide polymorphisms (SNPs) in these genes for the first time in a large Iberian populati...


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