Hereditary transthyretin amyloidosis (ATTRv) is a systemic disease caused by the accumulation of misfolded transthyretin (TTR). It usually presents with an adult-onset progressive axonal peripheral neuropathy and cardiomyopathy. In the central nervous system (CNS), variant TTR is produced by the choroid plexus and accumulates in the leptomeninges. CNS symptoms have been increasingly recognized in this populatio...
Made available in DSpace on 2020-12-10T16:37:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-01; FCT. Fundacao para a Ciencia e Tecnologia.Portugal; Packaging for frozen foods is characterized by technological and commercial development, but also leads to negative environmental impact. The present study assessed mock-ups developed by a packaging design method based on principles for sustainability ...