20 documents found, page 1 of 2
Non-Vitamin K Oral Anticoagulants Assessment in High Risk of Bleeding Patients ...
Silva Cunha, P; Viveiros Monteiro, A; Coutinho Cruz, M; Malveiro, P; Reis, JP; Portugal, G; Dias, A; Cruz Ferreira, R; Oliveira, MMAtrial fibrillation (AF) is commonly associated with advanced age and the presence of multiple, concomitant acute and chronic health conditions, placing this population at high risk for serious therapeutic side effects. Nonvitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in patients with atrial fibrillation. The purpose of this study was to investigate the effectivene...
Association Between Alcohol Intake and Cardiac Remodeling
Rodrigues, P; Santos-Ribeiro, S; Teodoro, T; Veloso Gomes, F; Leal, I; Reis, JP; Goff, DC; Gonçalves, A; Lima, JBackground: Alcohol-induced cardiotoxicity is incompletely understood. Specifically, the long-term impact of alcohol use on ventricular remodeling or dysfunction, its modulators, and effect thresholds among young adults remain controversial. Objectives: The authors sought to evaluate a potential relationship between alcohol intake and cardiac remodeling, assessed by echocardiography, over 20 years of follow-up....
Benign follicular tumors
Tellechea, O; Cardoso, JC; Reis, JP; Ramos, L; Gameiro, AR; Coutinho, I; Baptista, APBenign follicular tumors comprise a large and heterogeneous group of neoplasms that share a common histogenesis and display morphological features resembling one or several portions of the normal hair follicle, or recapitulate part of its embryological development. Most cases present it as clinically nondescript single lesions and essentially of dermatological relevance. Occasionally, however, these lesions be ...
Case for diagnosis
Cabral, AR; Coutinho, I; Reis, JPHuman scabies is an intensely pruritic skin infestation caused by Sarcoptes scabiei var. hominis. Crusted scabies (previously known as Norwegian scabies) is a rare form, very contagious and transmitted by direct contact with the skin. Despite being readily treatable, a delayed diagnosis often leads to widespread infestation of contacts, and therefore difficult to restrain. This case concerns a patient where der...
Adverse cutaneous reactions to epidermal growth factor receptor inhibitors: a s...
Santiago, F; Gonçalo, Margarida; Reis, JP; Figueiredo, ABACKGROUND: Cetuximab and erlotinib, epidermal growth factor receptor inhibitors, often cause peculiar adverse cutaneous reactions. OBJECTIVES: Our aim was to evaluate adverse cutaneous reactions and their management in patients undergoing treatment with cetuximab and erlotinib. PATIENTS AND METHODS: Between March/2005 and September/2009, we observed 14 patients with a mean age of 59.6 years undergoing treatmen...
Case for diagnosis
Santiago, F; Reis, JPThis report describes a patient with clinical and histopathological findings compatible with angiolymphoid hyperplasia with eosinophilia. This benign vascular hyperplasia should be recognized and differentiated from Kimura's disease.
Fibrous histiocytomas: histopathologic review of 95 cases.
Canelas, MM; Cardoso, JC; Andrade, PF; Reis, JP; Tellechea, OFibrous histiocytoma (FH) is a heterogeneous tumor composed of fibroblasts, histiocytes, and blood vessels. We conducted a retrospective histopathologic analysis of 95 biopsies, performed over the last 3.5 years, of fibrous histiocytomas to analyze the location, delimitation, epithelial changes, induction of folliculo-sebaceous structures, cellularity, vascularity, collagen pattern, and types of composite cells...
A propósito de um caso de espessamento cutâneo
Serra, S; Ambrósio, C; Salvador, MJ; Silva, J; Serra, D; Reis, JP; Malcata, ABThe authors present a clinical case of a 79 years old female patient, with a progressive cutaneous thickening of the face, trunk and limbs, lasting for 6 years. She also presented exertional dyspnea and intermittent solid dysphagia. The laboratory study identified IgG KAPA monoclonal protein and antinuclear antibodies with a speckled pattern. The nailfold capillaroscopy was normal. A detailed physical examinati...
Vasculite livedóide em doente com síndrome antifosfolípido
Serra, S; Saavedra, MJ; Salvador, MJ; Reis, JP; Malcata, ABThe authors present a clinical case of a 30 year old male patient admitted to the hospital for recurrent cyanosis and feet pain lasting for one year. In addition he presented bilateral purpuric lesions in the lateral maleolar region, one of which with ulceration. The finding of anticardiolipin antibodies associated with intraluminal thrombosis in the dermal vessels, allowed to conclude for Antiphospholipid synd...
Infundibulomatosis: A case report with immunohistochemical study and literature...
Cardoso, JC; Reis, JP; Figueiredo, P; Tellechea, OTumor of the follicular infundibulum was first described in 1961 by Mehregan and Butler in a patient presenting with multiple papules. It is more frequent, however, as an isolated lesion affecting mainly the face, neck, and upper trunk. Clinical presentation is variable, requiring histology for the diagnosis, which reveals typically a plate-like proliferation of keratinocytes in continuity with the epidermis an...