2 documents found, page 1 of 1
Renal macrophage infiltration is associated with a poor outcome in IgA nephropathy
Silva, Gyl Eanes Barros; Costa, Roberto Silva; Ravinal, Roberto Cuan; Ramalho, Leandra Naira Zambelli; Reis, Marlene Antonia dos; Moyses-Neto, MiguelOBJECTIVES: The objectives of our study were as follows: 1) to analyze the prognostic value of macrophage infiltration in primary IgA nephropathy (IgAN) and 2) to study the relationship between macrophages and other factors associated with the development of renal fibrosis, including mast cells, TGF-β1, α-SMA and NF-kB. METHODS: We analyzed 62 patients who had been diagnosed with IgAN between 1987 and...
Disseminated toxoplasmosis presenting as sepsis in two AIDS patients
Barbosa, Carlos José Dornas Gonçalves; Molina, Rodrigo Juliano; Souza, Murilo Barcelos de; Silva, Ana Cristina A.; Micheletti, Adilha RuaO presente relato descreve dois pacientes que apresentaram toxoplasmose aguda, disseminada e grave como primeira manifestação oportunista da síndrome da imunodeficiência adquirida. Os achados clínicos e laboratoriais foram similares aos de sepse ou choque séptico e, em ambos os casos houve evolução rápida para óbito. À necropsia, foi observada reação inflamatória e presença de taquizoítos e cistos de Toxoplasma...