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Aberrant hippocampal transmission and behavior in mice with a stargazin mutatio...

Caldeira, G. L.; Inácio, A.; Beltrão, N.; Barreto, C. A. V.; Rodrigues, M. V.; Rondão, T.; Macedo, R.; Gouveia, R. P.; Edfawy, M.; Guedes, J.; Cruz, B.

Mutations linked to neurodevelopmental disorders, such as intellectual disability (ID), are frequently found in genes that encode for proteins of the excitatory synapse. Transmembrane AMPA receptor regulatory proteins (TARPs) are AMPA receptor auxiliary proteins that regulate crucial aspects of receptor function. Here, we investigate a mutant form of the TARP family member stargazin, described in an ID patient....


Polar marine biology science in Portugal and Spain: Recent advances and future ...

Xavier, J.; Barbosa, Ana B.; Agustí, S.; Alonso-Sáez, L.; Alvito, P.; Ameneiro, J.; Ávila, C.; Baeta, A.; Canário, J.; Carmona, R.; Catry, P.; Ceia, F.

Polar marine ecosystems have global ecological and economic importance because of their unique biodiversity and their major role in climate processes and commercial fisheries, among others. Portugal and Spain have been highly active in a wide range of disciplines in marine biology of the Antarctic and the Arctic. The main aim of this paper is to provide a synopsis of some of the results and initiatives undertak...


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