Recently, biomedical engineering has seen significant advancements in nanomaterial-based scaffolds for tissue engineering and wound healing. Incorporating halochromic properties within these scaffolds has garnered substantial interest due to their real-time monitoring abilities for accessing tissue growth and regeneration. This review presents a comprehensive analysis of recent advancements in nanomaterial-base...
Background and aims Iron deficiency chlorosis (IDC) is a nutritional disorder impacting plants and is prevalent in calcareous alkaline soils, correspond- ing to 30% of the world’s arable land. IDC compro- mises iron uptake in crops such as soybean (Glycine max). To improve the effect of iron fertilisers, we sought to develop a nanotechnology-based interven- tion using polymeric nanoparticles (NPs) loaded with F...
Photothermal therapy has emerged as a new promising strategy for the management of cancer, either alone or combined with other therapeutics, such as chemotherapy. The use of nanoparticles for multimodal therapy can improve treatment performance and reduce drug doses and associated side effects. Here we propose the development of a novel multifunctional nanosystem based on solid lipid nanoparticles co-loaded wit...
Fungal diseases currently affect about a quarter of the population worldwide. Fungi infections caused by Candida albicans have been described as a significant concern to public health. The spectrum of clinical diseases caused by this fungi species range between vulvovaginal candidiasis, oral candidiasis, candidemia and mucositis. The emergence of resistance mechanisms towards antifungal therapy greatly hampers ...
In chronic wound (CW) scenarios, Staphylococcus aureus-induced infections are very prevalent. This leads to abnormal inflammatory processes, in which proteolytic enzymes, such as human neutrophil elastase (HNE), become highly expressed. Alanine-Alanine-Proline-Valine (AAPV) is an antimicrobial tetrapeptide capable of suppressing the HNE activity, restoring its expression to standard rates. Here, we proposed the...
The antimicrobial activity of two serine derived gemini cationic surfactants, amide (12Ser)2CON12 and ester (12Ser)2COO12, was tested using sensitive, E. coli ATCC 25922 and S. aureus ATCC 6538, and resistant, E. coli CTX M2, E. coli TEM CTX M9 and S. aureus ATCC 6538 and S. aureus MRSA ATCC 43300 Gram-positive and Gram-negative bacteria strains. Very low MIC values (5 μM) were found for the two resistant strai...