Made available in DSpace on 2022-05-01T08:44:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Medical Research Council; National Institutes of Health; Paramyxoviruses have a broad host range and geographic distribution, including human pathogens transmitted by bats, such as Nipah and Hendra viruses. In this study, we combined high-th...
Reinfection by the severe acute respiratory syndrome coronavirus type 2 (SARS-COV-2) has been reported in many countries, suggesting that the virus may continue to circulate among humans despite the possibility of local herd immunity due to massive previous infections. The emergence of variants of concern (VOC) that are more transmissible than the previous circulating ones has raised particular concerns on the ...
OxfordNanoporeTechnologiesfortechnicalsupportandQIAGENforsupport of the ZIBRA-2 (Zika in Brazil Real Time Analyses-Second Round)project with reagents and equipment. This work was supported by Decit/SCTIE/MoH and CNPq (440685/2016-8 and 440856/2016-7); by CAPES(88887.130716/2016-00, 88881.130825/2016-00, and 88887.130823/2016-00); by the European Union (EU) Horizon 2020 Programme through ZIKAlliance(PRES-005-FEX...
Public Health England; Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (302584/20115-3); Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo (203141/Z/16/Z. M.E.-Z,2018/14389-0), (204311/Z/16/Z); Wellcome Trust (ARSEQ-BEC-003163-2017); EMBO (ALTF376-2017); Universidad San Francisco de Quito; European Research Council (614725-PATHPHYLODYN); Medical Research Council (MR/L009528/1); Leverhulme Trust...
We conducted the genome sequencing and analysis of the first confirmed COVID-19 infections in Brazil. Rapid sequencing coupled with phylogenetic analyses in the context of travel history corroborate multiple independent importations from Italy and local spread during the initial stage of COVID-19 transmission in Brazil.
Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the genomic surveillance of viral outbreaks. An additional target enrichment step is generally needed for high-sensitivity pathogen identification in low-titre infections, yet available methods using PCR or capture probes can be limited by high c...
Funda??o Oswaldo Cruz. Instituto Le?nidas e Maria Deane. Laborat?rio de Ecologia de Doen?as Transmiss?veis na Amaz?nia. Manaus, AM, Brazil.; Universidade de S?o Paulo. Faculdade de Medicina. Instituto de Medicina Tropical. S?o Paulo, SP, Brazil.; Funda??o Oswaldo Cruz. Instituto Oswaldo Cruz. Laborat?rio de Flaviv?rus. Rio de Janeiro, RJ, Brazil / Universidade Federal de Minas Gerais. Instituto de Ci?ncias Biol...