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Cardiac mitochondrial dynamics, autophagy and regeneration are stirred by doxor...

Brandão, S. R.; Reis-Mendes, A.; Neuparth, M. J.; Carvalho, F.; Ferreira, R.; Costa, V. M.

Background: The chemotherapeutic agent doxorubicin (DOX) has been widely used in the treatment of solid tumors and hematological malignancies [1]. However, serious adverse side effects have emerged in patients treated with this drug, notably cardiotoxicity [2]. Moreover, aging is a risk factor for the development of cardiovascular diseases in cancer treated patients [3]. Objective: We herein aimed to evaluate t...

Date: 2023   |   Origin: Scientific Letters

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