33 documents found, page 1 of 4

Evaluating prebiotic potential

Mushrooms represent a promising source of bioactive macromolecules with numerous biological properties, including prebiotic potential. Although most studies focus on polysaccharide extracts, emerging evidence suggests that diverse mushroom macromolecules, such as proteins, peptides, fatty acids, and polyphenolic compounds, may also exert prebiotic effects. This chapter comprehensively explores the methodologica...

Antioxidant and neuroprotective potential of mushroom biomass: effects on ROS p...

Background: Mushrooms exhibit diverse bioactive compounds with prebiotic, immunomodulatory, antioxidant, and neuroprotective effects. These benefits may arise from direct metabolite absorption and gut microbiota modulation, a key regulator of brain health through the gut-brain axis1. This study explored the neuroprotective potential of macromolecules from the mushroom biomass (MB) from Trametes versicolor (TV),...

Neuroprotective effects of mushroom biomass: impact of serum-available and gut ...

Mushrooms are considered a next-generation food with numerous health-promoting properties, including prebiotic and neuroprotective effects. While most research studies focus on the polysaccharide fractions of mushroom-fruiting bodies1,2, this study investigates the neuroprotective potential of mushroom biomass (MB) from Trametes versicolor, Hericium erinaceus, and Pleurotus ostreatus considering the possible sy...

Bioaccessibility and bioavailability of bioactive compounds from mushroom bioma...

Mushrooms represent a promising source of bioactive compounds for functional food applications due to their rich nutritional profile, containing ?-glucans, ?-glucans, lectins, and other bioactive macromolecules. These macromolecules exhibit numerous health-promoting properties, such as prebiotic, immunomodulatory, anti-inflammatory, and antioxidant activities. While previous research has primarily focused on po...

Omega-3 and conjugated fatty acids impact on human microbiota modulation using ...

Background& aims: Gut microbiota has been gaining increasing attention and itsimportant role in the maintenance of a general good health condition is alreadyestablished. The potential of gut microbiota modulation through diet is animportant research focus to be considered. Lipids, as omega-3 fatty acids, arewell known for their beneficial role on organs and corresponding diseases.However, their impact on gut mi...

Comparative analysis of polysaccharide and nutritional composition of biologica...

This study chemically characterized three Pleurotus ostreatus fruiting bodies cultivated in the Iberian Peninsula under different conditions (biological and industrial), with emphasis on polysaccharide analysis. Comprehensive comparative data on cultivation-dependent nutritional variations will potentially improve their nutritional and therapeutic applications. Industrial mushrooms (POC and POA) contained signi...

Bioaccessibility and bioavailability of bioactive compounds from mushroom bioma...

Untangling sex differences in glia-to-neuron communication in chronic alcohol e...

Excessive alcohol consumption is global health challenge with profound neurobiological consequences. Our laboratory has shown that alcohol exposure induces reactive astrocytic changes, affecting gene expression, activity, and proliferation, while also altering microglial morphology and immune responses [1]. This study aims to characterise sex-specific effects of chronic alcohol consumption on the prefrontal cor...

The use of cecal samples from Wistar rats in in vitro fermentation to determine...

The influence of gut microbiota in the onset and development of several metabolic diseases, such as obesity and diabetes, has gained attention over the last few years. Indeed, diet plays an essential role in gut microbiota modulation. Western diet (WD), characterized by high-sugar and high-fat consumption, alters gut microbiome composition, diversity index, microbial relative levels, and functional pathways. Se...

Deciphering neuroimmune interactions in alcohol intake in mouse model of interm...

Excessive alcohol consumption continues to pose a significant global health challenge, with detrimental effects on millions of individuals. Our laboratory has shown that alcohol exposure triggers reactive changes in astrocytes, including alterations in gene expression, activity, and proliferation, while also affecting microglial morphology and immune responses. We are to characterizing the effects of chronic al...