2 documents found, page 1 of 1
Global, regional, and national burden of diabetes from 1990 to 2021, with proje...
Ong, Kanyin Liane; Stafford, Lauryn K.; McLaughlin, Susan A.; Boyko, Edward J.; Vollset, Stein Emil; Smith, Amanda E.; Dalton, Bronte E.; Duprey, JoeDiabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of ty...
Targeting NF-κB signaling pathway in cancer by dietary polyphenols
Khan, Haroon; Ullah, Hammad; Castilho, Paula Cristina Machado Ferreira; Gomila, Antoni Sureda; D'Onofrio, Grazia; Filosa, Rosanna; Wang, FangBeing a transcription factor, NF-κB regulates gene expressions involving cell survival and proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a central role in the development of inflammation and cancer. Thus, the down-regulation of NF-κB may be an exciting target in prevention and treatment of cancer. NF-κB could act as a tumor activator or tumor suppressant decided by ...