15 documents found, page 1 of 2
Addressing challenges to enhance clinical research in Portugal: insights from t...
Resende, Catarina; Abreu, Marta; Presa Ramos, José; Carda, José; Costa, Luís; Cardoso, Fátima; Pereira, Deolinda; Teixeira, Encarnação; Tonin, FernandaIntroduction Over the past decades, clinical research has evolved significantly, driven by advances in regulatory frameworks, technological innovations, and methodological approaches. In Portugal, while there has been progress - such as increased regulatory alignment with European standards and the adoption of digital trial management tools - various challenges remain. These may include, among others, limited a...
Assessment of calcinosis in Portuguese patients with systemic sclerosis: a mult...
Samões, Beatriz; Guimarães da Fonseca, Diogo; Beirão, Tiago; Costa, Flávio; Vieira, Romana; Terroso, Georgina; Ferreira, Raquel Miriam; Nicolau, RafaelaIntroduction/objectives: The study aims to define the clinical and subclinical calcinosis prevalence, the sensitivity of radiographed site and clinical method for its diagnosis, and the phenotype of Portuguese systemic sclerosis (SSc) patients with calcinosis. Method: A cross-sectional multicenter study was conducted with SSc patients fulfilling Leroy/Medsger 2001 or ACR/EULAR 2013 classification criteria, regi...
The safety and persistence of intravenous iloprost in systemic sclerosis
Martins, Patrícia; Dourado, Eduardo; Fonseca, João Eurico; Romão, Vasco C.; Resende, CatarinaIntroduction: Vasculopathy is a crucial feature of systemic sclerosis (SSc). It occurs in almost every patient with SSc, with Raynaud's phenomenon (RP) and digital ulcers (DU) having a great impact on the quality of patients' lives. Intravenous (IV) iloprost, a synthetic analogue of prostacyclin, is broadly used to treat RP and DU secondary to SSc. Currently, there is no standard protocol defined for the ilopro...
Biodiversity and health: investing in biodiversity protection towards health gains
Viegas, Carla; Moniz, Gabriela; Pargana, João; Marques, Susana; Resende, Catarina; Martins, Carla; Arez, Ana Paula; Ceratto, Nadia; Viegas, SusanaBiodiversity is declining faster than at any time in human history and the direct drivers of change in nature with the largest global impact are related to human activities: land and sea use changes; direct exploitation of organisms; climate change; pollution; and invasion of alien species. The One Health approach, and other holistic approaches, integrate human, animal, and plant health, as well as the health o...
Ten years of a systemic sclerosis clinic in a tertiary referral centre - insigh...
Martins, Patrícia; Dourado, Eduardo; Fonseca, João Eurico; Cordeiro, Inês; Romão, Vasco C.; Resende, CatarinaSystemic sclerosis (SSc) is an uncommon condition, with a wide range of manifestations, characterized by specific antibody production, vasculopathy and fibrosis of the skin and other internal organs. It is a complex disease, which is estimated to be rare in Portugal, although specific incidence data are missing. The aetiology of SSc remains unknown, but is likely to be multifactorial, involving genetic and envi...
Chronic thromboembolic pulmonary hypertension: initial experience of patients u...
Plácido, Rui; Guimarães, Tatiana; Jenkins, David; Cortez-Dias, Nuno; Couto Pereira, Sara Cristina; Campos, Paula; Mineiro, Ana; Lousada, NunoIntroduction and objectives: Pulmonary endarterectomy (PEA) is a potentially curative procedure in patients with chronic thromboembolic pulmonary hypertension (CTEPH). This study reports the initial experience of a Portuguese PH center with patients undergoing PEA at an international surgical reference center. Methods: Prospective observational study of consecutive CTEPH patients followed at a national PH cente...
Gender differences in clinical features and outcomes of a Portuguese systemic s...
Freitas, Raquel; Martins, Patrícia; Dourado, Eduardo; Santiago, Tânia; Guimarães, Francisca; Fernandes, Bruno Miguel; Garcia, Salomé; Samões, BeatrizEvidence for the role of sex in the clinical manifestations of systemic sclerosis (SSc) patients is emerging. Some multicenter cohorts have shown that male SSc patients have more severe disease and worse survival. To assess the differences in clinical manifestations and survival in Portuguese SSc patients according to gender. Data from male and female adult SSc patients included in the Rheumatic Diseases Portug...
Venous Thromboembolism in Pediatric Age: A 15 Year Retrospective Review
Andrade, Joana Verdelho; Magalhães, Joana; Resende, Catarina; Gomes, Dora; Laranjo, Gabriela; Campos, Joana; Santos, Elisabete; Faria, CristinaIntroduction: Pulmonary thromboembolism and deep venous thrombosis occur in pediatric age, with unknown incidence, morbidity and mortality. Our aim is to review the epidemiology, clinical presentation, complementary diagnostic tests and prognosis of patients with pulmonary thromboembolism and deep venous thrombosis.Material and Methods: Retrospective, descriptive and analytical study of pediatric patients admit...
Relatório de Estágio Curricular - DUROMIN – Equipamentos para Minas, Pedreiras ...
Resende, CatarinaA realização do estágio curricular enquadra-se no âmbito do programa curricular da Licenciatura em Gestão da Escola Superior de Tecnologia e Gestão do Instituto Politécnico da Guarda. Este estágio curricular realizou-se ao longo de 400 horas na empresa DUROMIN – Equipamentos para Minas, Pedreiras e Obras Públicas, Lda., na área financeira e também na área logística. O estágio é o primeiro grande passo para a en...
Depressão nos adolescentes – mito ou realidade?
Resende, Catarina; Santos, Elisabete; Santos, Paulo; Ferrão, AlziraIntrodução: A adolescência é um período de grandes mudanças a nível biopsicossocial, o que torna esta fase mais vulnerável a alterações psicológicas. A depressão surge como uma entidade clínica cada vez mais prevalente, podendo ser precursora de psicopatologia no adulto. Objetivos: Avaliar a prevalência e caracterizar a população de adolescentes com síndrome depressivo na consulta de adolescência. Material e mé...