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Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and C...
Petersen, BS; August, D; Abt, R; Alddafari, M; Atarod, L; Baris, S; Bhavsar, H; Brinkert, F; Buchta, M; Bulashevska, A; Chee, R; Cordeiro, AI; Dara, NBackground: In contrast to adult-onset inflammatory bowel disease (IBD), where many genetic loci have been shown to be involved in complex disease etiology, early-onset IBD (eoIBD) and associated syndromes can sometimes present as monogenic conditions. As a result, the clinical phenotype and ideal disease management in these patients often differ from those in adult-onset IBD. However, due to high costs and the...
Data: 2017
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Origem: Repositório do Centro Hospitalar de Lisboa Central, EPE