Epithelial cell migration is an essential response to enteric pathogens such as enteropathogenic Escherichia coli (EPEC). This study aimed to investigate the effects of EPEC infection on intestinal epithelial cell migration in vitro, as well as the involvement of type III secretion system (T3SS) and Rho GTPases. Crypt intestinal epithelial cells (IEC-6) were infected with EPEC strains (E2348/69, DescF, and the ...
The snake poisoning represents a public health problem, which is characterized by several systemic pathophysiologies, among which acute renal injury (AKI) is the most important. The pathogenesis of AKI induced by Botrópico poisoning is multifactorial and tends to be associated with direct nephrotoxicity, disseminated vascular coagulation and the activity of proteolytic enzymes that act on the structures of the ...