2 documents found, page 1 of 1
Fucoidan-based hydrogels particles as versatile carriers for diabetes treatment...
Reys, Lara L.; Silva, Simone S.; Soares da Costa, Diana; Reis, R. L.; Silva, Tiago H.There is a current lack of fully efficient therapies for diabetes mel-litus, a chronic disease where the metabolism of blood glucose isseverely hindered by a deficit in insulin or cell resistance to thishormone. Therefore, it is crucial to develop new therapeutic strat-egies to treat this disease, including devices for the controlleddelivery of insulin or encapsulation of insulin-producing cells. Inthis work, f...
Dual delivery of hydrophilic and hydrophobic drugs from chitosan/diatomaceous e...
López-Cebral, Rita; Peng, Guangjia; Reys, Lara L.; Silva, Simone Santos; Oliveira, Joaquim M.; Chen, Jie; Silva, Tiago José Quinteiros Lopes HenriquesOral administration of drugs presents important limitations, which are frequently not granted the importance that they really have. For instance, hepatic metabolism means an important drug loss, while some patients have their ability to swell highly compromised (i.e. unconsciousness, cancer...). Sublingual placement of an accurate Pharmaceutical Dosage Form is an attractive alternative. This work explores the u...