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Persistent Sydenham’s chorea is not associated with sustained lymphocyte dysfun...

Torres,Karen Cecília de Lima; Rocha,Natália Pessoa; Rezende,Vítor Bortolo de; Dutra,Walderez Ornelas; Gollob,Kenneth John; Cardoso,Francisco

The mechanisms involved in the symptoms of Sydenham’s chorea (SC) remain obscure. Taking into account the autoreactive antibody-mediated hypothesis of SC pathogenesis, the persistence of chorea may be associated with increased levels of B1 lymphocytes and other lymphocyte subsets. We evaluated lymphocyte subsets, including B1 and T cells, in patients with remitted (RSC) and persistent (PSC) SC by flow cytometry...

Date: 2016   |   Origin: Oasisbr
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