2 documents found, page 1 of 1
Microfluidic fabrication of gadolinium-doped hydroxyapatite for theragnostic ap...
Somoza, M.; Rial, R.; Liu, Z.; Llovo, I. F.; Reis, R. L.; Mosqueira, J.; Ruso, J. M.Among the several possible uses of nanoparticulated systems in biomedicine, their potential as theragnostic agents has received significant interest in recent times. In this work, we have taken advantage of the medical applications of Gadolinium as a contrast agent with the versatility and huge array of possibilities that microfluidics can help to create doped Hydroxyapatite nanoparticles with magnetic properti...
Mineralization of layer-by-layer ultrathin films containing microfluidic-produc...
Rial, R.; Costa, Rui Filipe Ramos; Reis, R. L.; Liu, Z.; Pashkuleva, I.; Ruso, J. M.We describe the assembly of layer-by-layer (LbL) ultrathin films containing bioactive hydroxyapatite (HAp) rod-shaped nanoparticles with mineralizing capacity. Monodisperse 96 nm long and 9 nm wide HAp nanorods with a surface charge of â 14 mV were produced with a microfluidic system. The negatively charged HAp nanorods were assembled with the polycation poly-L-lysine (PLL) in LbL fashion. The successful deposi...