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Rates of adverse events in patients with Ulcerative Colitis undergoing colectom...

Dragoni, Gabriele; Innocenti, Tommaso; Amiot, Aurelién; Castiglione, Fabiana; Melotti, Laura; Festa, Stefano; Savarino, Edoardo Vincenzo; Truyens, Marie

INTRODUCTION: Patients with ulcerative colitis (UC) receiving immunosuppressive drugs are at substantial risk of colectomy. We aimed to assess the risk of postoperative complications of tofacitinib exposure before colectomy in comparison with biologics. METHODS: A multicenter, retrospective, observational study was conducted in patients with UC who underwent total colectomy for medically refractory disease, exp...


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