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Yeast β-glucans and microalgal extracts modulate the immune response and gut mi...
Carballo, Carlos; Pinto, Patricia IS; Mateus, Ana; Berbel, Concha; Guerreiro, Claudia; Martinez-Blanch, Juan F.; Codoñer, Francisco M.; Mantecon, LaliaOne bottleneck to sustainability of fish aquaculture is the control of infectious diseases. Current trends include the preventive application of immunostimulants and prebiotics such as polysaccharides. The present study investigated how yeast β-glucan (Y), microalgal polysaccharide-enriched extracts (MAe) and whole Phaeodactylum tricornutum cells (MA) modulated the gut microbiome and stimulated the immune syste...
Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomics a...
Pinto, Patricia IS; Guerreiro, Claudia; Costa, Rita A.; Martinez-Blanch, Juan F.; Carballo, Carlos; Codoñer, Francisco M.; Manchado, ManuelPseudo-albinism is a pigmentation disorder observed in flatfish aquaculture with a complex, multi-factor aetiology. We tested the hypothesis that pigmentation abnormalities are an overt signal of more generalised modifications in tissue structure and function, using as a model the Senegalese sole and two important innate immune barriers, the skin and intestine, and their microbiomes. Stereological analyses in p...