7 documents found, page 1 of 1

Association between the use of female hormones and the thrombin generation: Cro...

Introduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CA...

Effects of vitamin D supplementation on cardiovascular risk factors in shift wo...

Objective: The present clinical study aims to describe protocol to evaluate the effects of vitamin D3 supplementation on the cardiovascular risk factors in a population of rotating shift workers. Design: A randomized, double-blind, placebo-controlled, parallel group clinical trial testing 2 oral dosages of cholecalciferol (14,000 IU and 28,000 IU per week) for 12 months. Setting: The primary outcome for evaluat...

Development and evaluation of a mobile decision support system for hypertension...

Background: Despite being an important cardiovascular risk factor, hypertension has low control levels worldwide. Computerized clinical decision support systems (CDSSs) might be effective in reducing blood pressure with a potential impact in reducing cardiovascular risk. Objective: The goal of the research was to evaluate the feasibility, usability, and utility of a CDSS, TeleHAS (tele–hipertensão arterial sist...

Development of the “Palliative Care” app to aid in patients care and assessment

Introduction: In patients receiving Palliative Care (PC), the need for care and the symptoms intensity gradually increase, as the main disease progresses. Objective: Describethe development of the multiplatform mobile app “Palliative Care”, to support the health professional who works in PC. Method: A multidisciplinary team proceeded withtheoretical revision, survey of software requirements, analysis of PC prof...

Brain natriuretic peptide based strategy to detect left ventricular dysfunction...

Background: Left ventricular dysfunction (LVd) is the main predictor of mortality in Chagas disease (ChD). Aims: To compare the diagnostic performance of the conventional approach (ECG and chest X-ray) in the recognition of LVd in ChD, with a new strategy, in which BNP is measured in patients with an abnormal ECG. Methods: Consecutive ChD patients recruited at an Outpatient Reference Center in Belo Horizonte, B...

In vivo inhibitory effect of anti-muscarinic autoantibodies on the parasympathe...

Treatment of Chagas cardiomyopathy.

Chagas’ disease (ChD), caused by the protozoa Trypanosoma cruzi (T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still bringsmuch misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in South America. It is an increasing worldwide problem due to t...