78 documents found, page 1 of 8
Exploring bio-based alternatives to cyclopentasiloxane: paving the way to promi...
Castro, Mariana; Roque, Catarina; Loureiro, Ana Isabel Sá; Guimarães, Diana Isabel Pereira; Silva, C.; Ribeiro, Artur; Cavaco-Paulo, ArturIn recent years, significant efforts have been made to identify suitable alternatives for silicones commonly used in daily cosmetic products. However, green alternatives have faced challenges in replicating the unique properties of silicone-based formulations, particularly cyclopentasiloxane, which continues to be widely used.This study explores the potential of six biosynthesized esters (heptyl heptanoate, hep...
Tunning antisolvent precipitation for the synthesis of lignin nanoparticles usi...
Mesquita, Ricardo Marchezan Farias de; Schneider, Willian Daniel Hahn; Longo, Vinicius; Baudel, Henrique Macedo; Diebold, Eduardo; Rencoret, JorgeLignin nanoparticles (LNPs) show great potential in UV-protectants, drugs carriers, encapsulation, supercapacitors, and others. This study proposes the development of an optimised LNP synthesis method by antisolvent precipitation, using lignin from persimmon tree pruning waste, green coconut waste, and sugarcane bagasse. The best synthesis conditions were determined evaluating the chemical composition and the p...
NADES-in-Oil Emulsions Enriched with Essential Oils for Cosmetic Application
Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, Joana Isabel ReisThis research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated in this study are based on previous formulations, consisting of 50 wt.% egg phosphatidylcholine (EPC), 20 wt.% ethanol, 20 wt.% olive oil (OlO), thyme oil (TO), or oregano oil (OrO), ...
Polycaprolactone-based fibrous scaffolds reinforced with cellulose nanocrystals...
Rocha, Joana M.; Sousa, Rui Pedro Carvalho Lima; Sousa, Diogo; Tohidi, Shafagh Dinparast; Ribeiro, Artur; Fangueiro, Raúl; Ferreira, Diana P.Anterior cruciate ligament (ACL) injuries pose significant challenges, driving the need for innovative repair strategies. Tissue engineering (TE) has emerged as a promising field for ACL injuries. Wet spinning is a filament production technique that enables precise control over filament alignment, diameter, and porosity, making it suitable for developing new scaffolds for ACL injuries. This study develops fibro...
Pioneering wound care solutions: triaxial wet-spun fibers with bioactive agents...
Miranda, Catarina Alexandra Fortuna Santos; Silva, Ana Francisca Gomes da; Evenou, Camille; Lamartine, Jérôme; Fromy, BerengereThe incidence of bacterial infections associated with chronic wounds (CWs) has increased in recent years. Thus, a triaxial wet-spun fibrous system (containing three layers) was produced for CW healing. The triaxial fibers were loaded with cinnamon leaf oil (CLO), endowed with high antibacterial, antioxidant and anti-inflammatory features, and an antimicrobial peptide alaninealanineprolinevaline (AAPV) capable o...
Lyocell/silver knitted fabrics for prospective diabetic foot ulcers treatment: ...
Tavares, Tânia Daniela Eugénio; Ribeiro, Artur; Bengoechea, Carlos; Rocha, Diana; Alcudia, Ana; Begines, Belén; Silva, C.; Antunes, Joana Isabel CostaDiabetic foot ulcers (DFUs) are a serious complication of diabetes, often resulting in infections and further health deterioration. Thus, the development of an approach combining different therapies in just one formulation to treat DFUs remains very challenging. Silver-plated polyamide fibers offer antimicrobial properties, while lyocell provides biodegradability, biocompatibility and moisture management abilit...
Biosynthesis of new amphiphilic esters with emulsifying properties for long-ter...
Roque, Catarina; Castro, Mariana; Castro, Tarsila Gabriel; Ribeiro, Artur; Silva, C.; Cavaco-Paulo, Artur; Noro, Jennifer MartinsIn this work, several amphiphilic compounds were successfully synthesized via lipase-catalysis: 2-(2-ethoxyethoxy)ethyloctanoate, 2-(2-ethoxyethoxy)ethyldecanoate, 2-(2-ethoxyethoxy)ethylpalmitate, (2-(2-ethoxyethoxy)ethyloleate) and (2-(2-ethoxyethoxy)ethyllinoleate). The reactions were carried out using octanoic acid, decanoic acid, palmitic acid, oleic acid, and linoleic acid, as the aliphatic compounds, and...
Laccase-catalyzed polymerized natural bioactives for enhanced mushroom tyrosina...
Costa, Diana; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Ribeiro, Artur; Silva, CarlaSkin hyperpigmentation disorders, such as melasma, are linked to excessive melanin production, primarily regulated by the enzyme tyrosinase (TYR). While current inhibitors like kojic acid (KA) are effective, they often cause adverse side effects, driving the search for safer andnatural alternatives. This study evaluated the TYR inhibitory potential of bioactive-rich extracts from acorn, cocoa, cork, and eucalyp...
Development of biomimetic human nails using electrospun keratin nanofibers and ...
Fernandes, Diana; Silva, Francisca; Santos, Daniela; Fernandes, Eduarda; Amaral, Maria; Baptista, Rosa; Ribeiro, Artur; Lopes, Carla; Lúcio, MarleneIntroduction: Nail infections, particularly onychomycosis, affect approximately 5.5% of the global population, significantly impacting quality of life. Beyond aesthetic concerns, these conditions cause discomfort, functional impairment, and psychological distress. A major challenge in treatment is the low transungual permeability of the nail plate, restricting drug penetration and reducing therapeutic efficacy....
Artificial tendons' responsiveness to mechanical stress and biological performa...
Oliveira, Bruna; Teixeira, Marta O.; Gonçalves, Sónia P.; Ribeiro, Artur; Silva, C.; Felgueiras, Helena PradoHand tendon ruptures have increased due to mechanical stress, degeneration, trauma, and repetitive motion. This study proposes an artificial tendon engineered from polymeric braids made of lyocell, biodegradable polyester, and polyethylene terephthalate, functionalized with natural cork extract. Cork extract 2, obtained by cork powder using hydroethanolic solvent in a planetary mixture, exhibited a phenolic con...