18 documents found, page 1 of 2
ZIKV Strains Elicit Different Inflammatory and Anti-Viral Responses in Microgli...
Oliveira, Fernanda Bellaniza Caminha de; Freire, Vanessa Paola Alves Sampaio de Sá; Coelho, Sharton Vinicius Antunes; Meuren, Lana MonteiroIn recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3...
Pocket Rehab – programa de reabilitação baseado em mHealth para pacientes com d...
Cipriano Júnior, Gerson; Cahalin, Lawrence P.; Hansen, Dominique; Meira, Augusto; Kaway, Fernando; State, Radu; Durigan, João Luiz QuagliottiPacientes com doença cardiovascular e fatores de risco para doença cardiovascular (DCV) têm sido afetados com mais frequência e mais gravemente pelo novo coronavírus. Isso agravou o cenário anterior de subutilização dos programas de reabilitação cardiovascular (RCV) antes da pandemia, exigindo alternativas otimizadas de RCV, como por exemplo aquelas baseadas em aplicativos móveis (mHeath), não apenas por gerar ...
A nymphalid-infecting group I Alphabaculovirus isolated from the major passion ...
Ribeiro, Bergmann Morais; Santos, Ethiane Rozo dos; Trentin, Luana Beló; Silva, Leonardo Assis da; Melo, Fernando Lucas de; Kitajima, Elliot WatanabeBaculoviruses are capable of infecting a wide diversity of insect pests. In the 1990s, the Dione juno nucleopolyhedrovirus (DijuNPV) was isolated from larvae of the major passionfruit defoliator pest Dione juno juno (Nymphalidae) and described at ultrastructural and pathological levels. In this study, the complete genome sequence of DijuNPV was determined and analyzed. The circular genome presents 122,075 bp wi...
Genomic analysis of a cypovirus isolated from the eucalyptus brown looper, Thyr...
Horta, André Ballerini [UNESP]; Ardisson-Araujo, Daniel Mendes Pereira; da Silva, Leonardo Assis; de Melo, Fernando Lucas; da Silva Morgado, FabricioMade available in DSpace on 2018-12-11T17:20:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-15; Fundação de Apoio à Pesquisa do Distrito Federal; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The eucalyptus brown looper, Thyrinteina arnobia (Stoll, 1782) (Lepidoptera: Geometridae), is the main lepidopteran defoliator of eucalyptus plantations in Brazil. Outbreaks of this in...
Draft genome sequence of Bacillus thuringiensis 147, a Brazilian strain with hi...
Barbosa, Luiz Carlos Bertucci; Farias, Débora Lopes; Silva, Isabella de Moraes Guimarães; Melo, Fernando Lucas; Ribeiro, Bergmann MoraisBacillus thuringiensisis a ubiquitous Gram-positive and sporulating bacterium. Its crystals and secreted toxins are useful tools against larvae of diverse insect orders and, as a consequence, an alternative to recalcitrant chemical insecticides. We report here the draft genome sequence ofB. thuringiensis147, a strain isolated from Brazil and with high insecticidal activity. The assembled genome contained 6,167,...
Structural and ultrastructural changes during the infection of UFL-AG-286 cells...
Pombo, Vivian; Velloso, Lucas Malard; Ribeiro, Bergmann Morais; Báo, Sônia NairDuring infection of the permissive insect cell line UFL-AG-286 by the baculovirus Anticarsia gemmatalis nucleopolyhedrovirus (AgMNPV-2D) several morphological changes occur. By 12 h postinfection (h p.i.), the infected cells became round and exhibited a decrease in the number of cytoplasmic projections. By 24 h p.i., it was possible to detect a virogenic stroma inside the cell nucleus, and after 48 h p.i., poly...
The genome sequence of Pseudoplusia includens single nucleopolyhedrovirus and a...
Craveiro, Saluana Rocha; Inglis, Peter W.; Togawa, Roberto Coiti; Grynberg, Priscila; Melo, Fernando Lucas; Ribeiro, Zilda Maria de AraújoBackground: Pseudoplusia includens single nucleopolyhedrovirus (PsinSNPV-IE) is a baculovirus recently identified in our laboratory, with high pathogenicity to the soybean looper, Chrysodeixis includens (Lepidoptera: Noctuidae) (Walker, 1858). In Brazil, the C. includens caterpillar is an emerging pest and has caused significant losses in soybean and cotton crops. The PsinSNPV genome was determined and the phyl...
New binding site conformations of the dengue virus NS3 Protease accessed by mol...
Almeida, Hugo de; Bastos, Izabela Marques Dourado; Ribeiro, Bergmann Morais; Maigret, Bernard; Santana, Jaime Martins deDengue fever is caused by four distinct serotypes of the dengue virus (DENV1-4), and is estimated to affect over 500 million people every year. Presently, there are no vaccines or antiviral treatments for this disease. Among the possible targets to fight dengue fever is the viral NS3 protease (NS3PRO), which is in part responsible for viral processing and replication. It is now widely recognized that virtual sc...
A betabaculovirus encoding a gp64 homolog
Araújo, Daniel Mendes Pereira Ardisson de; Pereira, Bruna T.; Melo, Fernando Lucas; Ribeiro, Bergmann Morais; Báo, Sônia NairBackground: A betabaculovirus (DisaGV) was isolated from Diatraea saccharalis (Lepidoptera: Crambidae), one of the most important insect pests of the sugarcane and other monocot cultures in Brazil. Results: The complete genome sequence of DisaGV was determined using the 454-pyrosequencing method. The genome was 98,392 bp long, which makes it the smallest lepidopteran-infecting baculovirus sequenced to date. It ...
A baculovirus-mediated strategy for full-length plant virus coat protein expres...
Araújo, Daniel Mendes Pereira Ardisson de; Rocha, Juliana Ribeiro; Costa, Márcio Hedil Oliveira da; Bocca, Anamélia Lorenzetti; Dusi, André NepomucenoBackground: Garlic production is severely affected by virus infection, causing a decrease in productivity and quality. There are no virus-free cultivars and garlic-infecting viruses are difficult to purify, which make specific antibody production very laborious. Since high quality antisera against plant viruses are important tools for serological detection, we have developed a method to express and purify full-...