93 documents found, page 1 of 10

Strategies for Research Capacity Building by Family Physicians in Primary Healt...

Introduction: The qualities of primary healthcare (PHC) make it a very relevant environment for research; however, there is still work to be done to enhance the research capabilities of family physicians in healthcare units. Considering there is no ongoing review that specifically addresses this objective, the proposed goal of this scoping review is to determine the depth of the literature on the current strate...

Chromatographic Methods for Detection and Quantification of Pyrrolizidine Alkal...

Pyrrolizidine alkaloids (PAs) are natural toxins produced by some plants that gained special interest due to their potential hazardous effects in humans and animals. These substances have been found in wild flora, herbal medicines and food products raising health concerns. Recently, maximum concentration levels of PAs were established for some food products; however, maximum daily intake frequently surpasses th...

Impact of outpatient adaptation to home mechanical ventilation on health-relate...

"Background: Home mechanical ventilation (HMV) is indicated in patients with severe hypercapnic COPD. Initiation of HMV commonly occurs during an inpatient period, but there has been increasing interest for outpatient adaptation. This study aimed to evaluate the outpatient initiation and adaptation of HMV and its impact on health-related quality of life (HRQoL) in patients with severe COPD. Methods: A single-gr...

Intrauterine Exposure to Phthalates and Child Growth in the First Year of Life:...

Phthalates are among the endocrine-disrupting compounds with higher widespread in daily life. Our objective was to assess the associations between maternal exposure to phthalates assessed by urinary phthalate metabolites and growth at birth and in the first year of life. The BiTwin cohort (479 single and 246 multiple pregnancies) was recruited as part of the HEALS project (2017–2019). Evaluations were conducted...

Measuring Adherence to Inhaled Control Medication in Patients with Asthma: Comp...

Background: Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of share...

Are problematic eating behaviors from 4- to 7-year-old explained by genetic, sh...

Studies based on twins are ideal to disentangle the relative contribution of different factors in the development of eating behaviors. This study aims to evaluate if changes in problematic eating behaviors from 4 to 7 years old are more influenced by the genetics, the shared environment of twins, or by individual characteristics of each twin. A total of 86 caregivers (mostly mothers) of twins from the Generatio...

Role of phthalates on adiposity: Epidemiological evidence

Overweight and obesity in adults have become a priority many decades ago, however, it remains one of the critical problems in public health around the world. It is also increasingly prevalent in children and adolescents and in the last three decades child obesity rates have tripled to approximately 17% in children aged between 2 to 19 years, and to 32% of overweight and obesity combined. Phthalates are classifi...

Early life exposures are associated with appetitive traits in infancy: findings...

Purpose To determine the stability of appetitive traits during infancy and their association with early life exposures. Methods Participants were from the BiTwin birth cohort (longitudinal study of Portuguese infants). Appetitive traits at 3 months were measured using the Baby Eating Behaviour Questionnaire (n = 347) and at 12 months with the Children’s Eating Behaviour Questionnaire for toddlers (n = 325). Sta...

Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Rev...

Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Rev...

Breast cancer (BC) is the most common malignancy and the second cause of cancer-specific death in women from high-income countries. Recently, gut microbiota dysbiosis emerged as a key player that may directly and/or indirectly influence development, treatment, and prognosis of BC through diverse biological processes: host cell proliferation and death, immune system function, chronic inflammation, oncogenic sign...