Within the discipline of respiratory medicine, there is a growing recognition of the relevance of breathing pattern disorders. Breathing pattern disorder, or dysfunctional breathing, is commonly characterized by an abnormal breathing pattern resulting in respiratory and non-respiratory symptoms, which may occur secondary to diseases or in its absence. The underlying mechanisms can be physiological (e.g. lung di...
A ciência encontra-se atualmente, numa fase de forte evolução e expansão. Isto muito devido ao desenvolvimento exponencial das tecnologias e da explosão de conhecimento e à facilidade na partilha de informação à escala global. A Paleontologia não é exceção e, desde o século passado que têm vindo a mostrar uma forte ligação multidisciplinar com outras áreas científicas, com as quais prosperam cada vez mais, como...
Metastatic calcinosis is an uncommon condition characterized by diffuse soft tissue calcification, which may occur with advanced chronic kidney disease (CKD), typically in those undergoing kidney replacement therapy (1, 2). Deposits usually appear around large joints such as the elbow, hip, and shoulder. Periarticular deposits may lead to arthralgia, reduced joint mobility, and neurovascular symptoms. Sustained...
With the world's increasing consumption of raw materials, many of them related to electronic systems and devices, it is of paramount importance to develop new generation of materials with improved performance, multifunctionality and recyclability. Intimately connected to this concern arises the use of production techniques that generate less waste and are compatible with the Internet of Things, IoT, and Industr...
The focus of this research is a qualitative study of mineralogical and chemical changes in plutonic mafic rock samples after exposure to a CO2-rich brine, under supercritical conditions (SC), to clarify the behavior of brine and rock in the initial stages of mineral carbonation. The studied rock consists of a gabbro-anorthosite from the Odivelas massif, in southern Portugal. The sample was exposed to a SC CO2-r...
Background: The synthetic drug butylone (2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one, BTL) is a chiral cathinone consumed in the form of racemate [1]. After consumption, BTL is metabolized and excreted along with its metabolites, and its residues are carried by sewerage systems to wastewater treatment plants (WWTPs) [2]. Both human metabolism and biodegradation in WWTPs may be enantioselective causing...
Background: The excessive use of psychoactive substances (PAS) is a global problem that directly and indirectly affects human, animal health and environment [1], related with “one health” concept. These substances and their metabolites enter in the wastewater through human excretion and consequently into water systems. The sewage sludge produced in wastewater treatment plants can be used as amendment in agricul...
Background: New psychoactive substances (NPS) represent an increasing human health and environmental concern. Despite the efforts to control their production and consumption, new molecules are identified every year. Consequently, their presence in water bodies has been reported raising concern due to potential negative impacts on non-target species such as fish [1], including the synthetic cathinone butylone (B...
Background: Tea and herbal infusions (THIs) consumption is recognized for its beneficial effects, which are attributed to the antioxidant properties of phenolic compounds [1–3].The wide diversity of THIs available in market and the absence or failure in quality control can expose the population to health risks [3]. Moreover, uncontrolled consumption may cause toxicity or lack of the expected benefits. Therefore...
Background: Synthetic cathinones (SC) are a group of novel illicit psychotropic substances that have been found in the aquatic environment at low concentrations [1] and nonetheless they can impact aquatic invertebrates [2]. SC can pose unwanted diverse adverse effects such as behavioral toxicity to non-target organisms [3]. The 3,4-methylenedioxypyrovalerone (MDPV) is a chiral SC with psychotropic properties si...