10 documents found, page 1 of 1
Corrigendum: Methylmercury impact on adult neurogenesis: is the worst yet to co...
Raposo, Ramon da Silva; Pinto, Daniel Vieira; Moreira, Ricardo; Dias, Ronaldo Pereira; Ribeiro, Carlos Alberto Fontes; Oriá, Reinaldo Barreto[This corrects the article DOI: 10.3389/fnagi.2020.591601.].
Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recen...
Raposo, Ramon da Silva; Pinto, Daniel Vieira; Moreira, Ricardo; Dias, Ronaldo Pereira; Ribeiro, Carlos Alberto Fontes; Oriá, Reinaldo BarretoWorldwide environmental tragedies of anthropogenic origin causing massive release of metals and other pollutants have been increasing considerably. These pollution outbreaks affect the ecosystems and impact human health. Among those tragedies, recent large-scale environmental disasters in Brazil strongly affected riverside populations, leading to high-risk exposure to methylmercury (MeHg). MeHg is highly neurot...
Assessment of Health-Related Quality of Life using the EQ-5D-3L in Individuals ...
Cardoso, Ana Filipa dos Reis Marques; Cruz, Rui Santos; Queirós, Paulo Joaquim Pina; Ribeiro, Carlos Alberto Fontes; Santiago, LuizThe daily experience with type 2 diabetes mellitus (T2DM) has significant adverse effects on health-related quality of life (HRQoL). HRQoL assessment is essential for measuring the impact of the disease on the patient and selecting individualized strategies. Generic measures for assessing HRQoL are very useful because, unlike specific measurement instruments, they allow for the comparison with other instruments...
Cultural Adaptation and Psychometric Properties of the Portuguese Version of th...
Amaral, António Fernando Salgueiro; Cardoso, Ana Filipa dos Reis Marques; Queirós, Paulo Joaquim Pina; Ribeiro, Carlos Alberto FontesBackground: Self-care is a nursing sensitive outcome. In Portugal there is a lack of validated scales to assess self-care. Scales have their own validation methods to be used in cultural contexts which are different from their original contexts. Aim: To translate, adapt, validate, and assess the psychometric properties of the Therapeutic Self-Care Scale (Doran & Sidani, 2005) for the Portuguese population. Meth...
Adaptação cultural e propriedades psicométricas da versão portuguesa da Therape...
Cardoso, Ana Filipa dos Reis Marques; Amaral, António Fernando Salgueiro; Queirós, Paulo Joaquim Pina; Ribeiro, Carlos Alberto FontesAcrescentar.
Validation and psychometrics of the Therapeutic Self-care instrument for the Po...
Cardoso, Ana Filipa dos Reis Marques; Amaral, António Fernando Salgueiro; Queirós, Paulo Joaquim Pina; Ribeiro, Carlos Alberto FontesAcrescentar.
Therapeutic added value
Ribeiro, Carlos Alberto FontesThe Added Therapeutic Value (ATV) means a better efficacy, safety and / or convenience of a drug in comparison with the best therapeutic alternative till now.ATV can also signify the drug effect with an acceptable benefit / risk ratio to a therapeutic necessity in a clinical indication without drugs.The demonstration of the ATV,which is a real therapeutic innovation and not only a commercial or technological in...
Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adr...
Cavadas, Cláudia; Grand, Daniela; Mosimann, François; Cotrim, Maria Dulce; Ribeiro, Carlos Alberto Fontes; Brunner, Hans R.; Grouzmann, EricThe aim of the present work was to study the effect of angiotensin II (Ang II) on catecholamines and neuropeptide Y (NPY) release in primary cultures of human adrenal chromaffin cells. Ang II stimulates norepinephrine (NE), epinephrine (EP) and NPY release from perifused chromaffin cells by 3-, 2- and 12-fold, respectively. The NPY release is more sustained than that of catecholamines. We found that the recepto...
NPY regulates catecholamine secretion from human adrenal chromaffin cells
Cavadas, Cláudia; Silva, António P.; Mosimann, François; Cotrim, Maria Dulce; Ribeiro, Carlos Alberto Fontes; Brunner, Hans R.; Grouzmann, EricThe aim of the present work was to find out whether NPY synthesized in human adrenal chromaffin cells controls in an autocrine/paracrine fashion the release of catecholamines by these cells. Accordingly, the constitutive and regulated release of both NPY and catecholamines was measured simultaneously in cultured human chromaffin cells. In addition, by using both RT-PCR and a combination of specific agonists and...
Receptores Adrenérgicos Alfa1 e Alfa2 e Fluxos de Cálcio na Artéria Uterina Humana
Ribeiro, Carlos Alberto FontesO nosso trabalho pretendeu caracterizar os receptores adrenérgicos e na artéria uterina humana e asua relação com os fluxos transmembranares de Ca++. 1.º- Obtivemos valores de pD2 e pA2 para agonistas e antagonistas que indicam a presença de receptores adrenérgicos a1 e a2. Este facto foi também demonstrado por métodos bioquímicos: a ligação da 3H-prazosina e da 3H-ioimbina às membranas celulares foi estereospe...