111 documents found, page 1 of 12
Quando a História entra pela porta ao lado: pensamento histórico e cidadania em...
Ribeiro, CláudiaEste artigo analisa a disciplina de Área de Integração, nos cursos profissionais, como espaço de desenvolvimento da literacia histórica e da cidadania crítica. A partir das Aprendizagens Essenciais e de autores da didática da História, argumenta-se que a História pode ser mobilizada para interpretar temas como democracia, Europa e sustentabilidade. A interdisciplinaridade da disciplina é discutida como oportuni...
Quando a História entra pela porta ao lado: pensamento histórico e cidadania em...
Ribeiro, CláudiaEste artigo analisa a disciplina de Área de Integração, nos cursos profissionais, como espaço de desenvolvimento da literacia histórica e da cidadania crítica. A partir das Aprendizagens Essenciais e de autores da didática da História, argumenta-se que a História pode ser mobilizada para interpretar temas como democracia, Europa e sustentabilidade. A interdisciplinaridade da disciplina é discutida como oportuni...
Analysis of multiple pesticide and endocrine disruptor residues in drinking wat...
Fernandes, Diana; Gorito, Ana; Ribeiro, Ana Rita; Ribeiro, CláudiaBackground: The presence of pesticide residues and endocrine disruptors in sources used for drinking water abstraction has become a significant concern nowadays [1,2]. These substances pose risks to the environment, biodiversity, and public health. Consequently, monitoring these compounds in drinking water is crucial to maintaining their quality and safety. Therefore, there is a need to develop sensitive analyt...
Enantioselective liquid chromatography method for the simultaneous determinatio...
Suordem, Beatriz; Marrero, Joaquín; Gorito, Ana; Ribeiro, Cláudia; L. Ribeiro, Ana RitaBackground: Fungicides are organic compounds, many of them chiral, used in various applications such as medicines, personal care products, agrochemicals and industry. Although they have beneficial effects in controlling fungal plagues and treating diseases, their widespread use has led to their detection in the environment [1-3]. As a result, fungicide contamination is increasingly a global environmental concer...
Fluoroquinolones: a preliminary study on optimized extraction and chromatograph...
Carvalho, Ana Rita; Vidal, Renata; Gonçalves, Virgínia M. F.; Maia, Alexandra S.; L. Ribeiro, Ana Rita; Ribeiro, CláudiaBackground: Fluoroquinolones (FQs) are a widely prescribed class of antibiotics, used in both human and veterinary medicine, commonly administered for prophylactic and therapeutic purposes [1]. Due to their extensive use and excretion in both unmetabolized form and metabolites, FQs and their metabolites persist in aquatic environments. As a result, these compounds are frequently detected in surface and groundwa...
Exploring the toxicity effects of 3-chloromethcathinone (3-CMC) on the morphoph...
António, João; Langa, Ivan; Carvalho, Ana; Vidal, Renata; Tiritan, Maria; Ribeiro, CláudiaBackground: The constant discharge of several potentially harmful compounds to the environment raises significant concerns about the risk of toxicity to non-target organisms and human health [1,2]. The 3-chloromethcathinone (3-CMC) is a chiral synthetic cathinone belonging to the group of new psychoactive substances (NPS) [3]. After consumption, this substance and/or its metabolites are excreted in urine, reach...
Preliminary data on the ecotoxicity effects of the novel synthetic cathinone 3,...
Pérez-Pereira, Ariana; Ribeiro, Ondina; Félix, Luís; Tiritan, Maria; Ribeiro, Cláudia; Carrola, JoãoBackground: The use of synthetic cathinones (SC) for recreational purposes has become increasingly common among young individuals in recent years [1]. As a result, SC have been detected in aquatic environments even at low concentrations (between ng L‒1 to µg L‒1) [2] that can negatively impact freshwater vertebrates [3]. Since SC are designed to affect the nervous system, they could potentially cause unpredicta...
Effects on apoptosis and neurotransmitters after exposure to 3-chloromethcathin...
Ribeiro, Ondina; Félix, Luís; Ribeiro, Cláudia; Soares Carrola, JoãoBackground: Synthetic cathinones are a class of new psychoactive substances (NPS) widely consumed worldwide. Their large-scale production and constant structural modifications lead to the emergence of new NPS every year. 3-Chloromethcathinone (3-CMC) was first identified on the European market in 2014 and is a halogenated and N-alkylated derivative of cathinone [1]. 3-CMC has a chiral centre, giving rise to two...
Ecotoxicity effects of 3-chloromethcathinone (3-CMC) on the swimming behaviour ...
António, João; Langa, Ivan; Carvalho, Ana; Vidal, Renata; Tiritan, Maria; Ribeiro, CláudiaBackground: The continuous release of various compounds can have potentially harmful effects on non-target organisms, raising concerns about the ecosystem and human health (1,2). 3-chloromethcathinone (3-CMC) is a chiral synthetic cathinone, classified as a new psychoactive substance (NPS) with similar effects to amphetamines and posing potential toxicological risks (3). After consumption, 3-CMC and its met...
Enantiomeric profiling of ketamine in street samples for recreational use
Varela, Inês; Milhazes, Nuno; Martins, Daniel; Gonçalves, Virgínia; Tiritan, Maria Elizabeth; Ribeiro, CláudiaBackground: While ketamine (KET) has gained increasing scientific attention for its novel therapeutic applications, there has also been a parallel global rise in its non-medical, recreational use. [1]. Due to its effects on the central nervous system—such as dissociation, perceptual alterations, and its well-known anesthetic properties—KET is frequently used recreationally for its psychoactive effects. [2]. As ...