Azole fungicides are commonly used in sawmills to protect wood against the wood-destroying basidiomycete fungi. Azole-resistant Aspergillus section Fumigati has previously been identified in these environments. Here we aimed to establish a sampling protocol to efficiently isolate Aspergillus section Fumigati in woodworking environments. The sampling campaign was conducted between December 2022 and November 2023...
Background: Severe acute respiratory syndrome coronavirus 2 immunoglobulin G (SARS-CoV-2-IgG) antibodies have been widely used to assist clinical diagnosis and occupational exposure risks. Objectives: This study aimed to estimate SARS-CoV-2 IgG levels acquired due to different vaccination schemes. Materials and methods: A retrospective study was performed on volunteers from the Instituto Politécnico de Lisboa. ...
Playgrounds are public spaces that offer recreational opportunities for hundreds of people, including children, young people, adults, and the elderly. Numerous pathogenic bacteria have been described in the literature as etiologic agents of several infections, with distinct manifestations and clinical outcomes, particularly affecting children's health. This systematic review aims to perform a scoping review of ...
Introdução – O Staphylococcus aureus resistente à meticilina (MRSA) tem-se disseminado globalmente, tornando-se endémico em muitos hospitais e comunidades. Além da meticilina, diversas estirpes de S. aureus têm mostrado resistência a uma variedade de outros antibióticos. Esta resistência é conferida por genes cuja presença e expressão são facilitadas por uma alta taxa de recombinação genética e pela capacidade ...
In the scope of the European Union (EU) human biomonitoring initiative, a multicentric study on different occupational settings from several European countries was performed, to provide information on occupational exposure to hexavalent chromium [Cr(VI)], a known lung carcinogen. Biomonitoring approaches were used to obtain exposure data to support the implementation of new risk management measures and policy a...
Background/Objectives: Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (DNMT1, DNMT3A, and DNMT3B) in AMD patients and explore divergent expression patterns across different stages of AMD. Methods: Thirty-eight AMD patients were prospe...
O mechanistic target of rapamycin (mTOR) é uma quinase que regula o crescimento, proliferação e sobrevivência celulares. A desregulação da via de mTOR está presente em diversas patologias, sendo a sua hiperativação observada em mais de 70% de cancros humanos, incluindo cancro gástrico (CG). Apesar de existirem atualmente diversos inibidores de mTOR (mTORi), a sua utilização clínica ainda é limitada devido à ele...
Portugal’s wood industry employs over 80,000 people and comprises about 16,600 enterprises in 2021. Sawmill workers are exposed to several occupational hazards, including microorganisms. Health problems have been documented by workers exposed to wood dust infected with fungi. A fungal priority pathogens list (WHO FPPL) was recently released by the WHO. It prioritizes fungal pathogens based on their perceived pu...
Background: Wastewater treatment plants (WWTPs) are crucial in the scope of European Commission circular economy implementation. However, bioaerosol production may be a hazard to occupational and public health. A scoping review regarding microbial contamination exposure assessment in WWTPs was performed. Methods: This study was performed through PRISMA methodology in PubMed, Scopus, and Web of Science. Results:...
Background: Serological screening is crucial for the prevention of infection, ensuring the maintenance of the worker’s health, and thus promoting occupational health. It was reported that SARS-CoV-2 can survive in aerosols and on dry surfaces for several days to weeks. Objectives: We aimed to apply an integrated approach to Occupational Health to tackle the COVID-19 pandemic. Materials and methods: We performed...