8 documents found, page 1 of 1
Improvement of the in vitro cytotoxic effect on HT-29 colon cancer cells by com...
Falcão, Soraia; Duarte, Diana; Diallo, Moustapha; Santos, Joana B.; Ribeiro, Eduarda; Vale, Nuno; Vilas-Boas, MiguelCancer is regard as one of the key factors of mortality and morbidity in the world. Treatment is mainly based on chemotherapeutic drugs that, when used in targeted therapies, have serious side effects. 5-fluorouracil (5-FU) is a drug commonly used against colorectal cancer (CRC), despite its side effects. Combination of this compound with natural products is a promising source in cancer treatment research. In r...
Smart cities using crowdsensing and geoferenced notifications
Miranda, Rui Pedro Mesquita; Ribeiro, Eduarda; Durães, Dalila; Peixoto, Hugo; Machado, Ricardo J.; Abelha, António; Machado, José ManuelAs the internet and the Internet of Things continue to expand, the idea of Smart Cities has begun to take hold. Smart Cities use connected devices and data to improve the environment and quality of life of their citizens. Technologies such as crowdsensing and geofencing allow citizens to contribute to initiatives and receive notifications when near areas of interest, respectively. This paper presents a systemat...
Survey for big data platforms and resources management for smart cities
Alves, Carlos Manuel Ferreira; Chaves, António; Rodrigues, Carla; Ribeiro, Eduarda; Silva, António José Linhares; Durães, Dalila; Machado, José ManuelCurrently, smart cities are a hot topic and their tendency will be to optimize resources and promote efficient strategies for the preservation of the planet as well as to increase the quality of life of its inhabitants. In this sense, this research presents an initial component of investigation about Big Data Platforms for Smart Cities in order to be implemented in integrated and innovative solutions for develo...
Who the fuck is Manu Gavassi? Um estudo de caso sobre o fenômeno Manu Gavassi d...
Ribeiro, EduardaSubmitted by Chaline Barbosa (chaline@upf.br) on 2021-06-08T19:09:33Z No. of bitstreams: 1 PF2020Eduarda Ribeiro.pdf: 2070818 bytes, checksum: 86be7499879a4f21fc20090b108a5d36 (MD5); Made available in DSpace on 2021-06-08T19:09:33Z (GMT). No. of bitstreams: 1 PF2020Eduarda Ribeiro.pdf: 2070818 bytes, checksum: 86be7499879a4f21fc20090b108a5d36 (MD5) Previous issue date: 2020-12-03; O presente estudo tem como obj...
Candida albicans adaptation on simulated human body fluids under different pH
Barbosa, Ana; Araújo, Daniela; Ribeiro, Eduarda; Henriques, Mariana; Silva, Sónia CarinaCandida albicans remains the most problematic of all Candida species, causing severe infections. Adaptation to different human body niches, such oral and urinary tracts, has been shown to be essential for survival and critical for virulence of C. albicans. Thus, the present work aimed to study the behaviour of C. albicans on simulated human body fluids (artificial saliva and urine) at different values of pH (pH...
A study of some hepatic immunological markers, iron load and virus genotype in ...
Cardoso, Elsa M.; Duarte, Miguel A.; Ribeiro, Eduarda; Rodrigues, Pedro; Hultcrantz, Rolf; Sampaio, Paula; Ehrlich, Rachel; Carvalho, João; Fraga, JoséBACKGROUND/AIMS: Host factors that may influence progression of hepatitis C infection to chronic hepatitis include T-cell responses and iron accumulation. We evaluated the hepatic expression of immunological markers relevant for a cytotoxic response in relation to viral and HFE genotype. METHODS: Frozen liver biopsies were obtained at diagnosis from 28 HFE genotyped patients. Sections stained for CD8, MHC-I, be...
Increased hepatic iron in mice lacking classical MHC class I molecules.
Cardoso, Elsa M.; Macedo, Maria G.; Rohrlich, Pierre; Ribeiro, Eduarda; Silva, Manuel T.; Lemonnier, François A.; de Sousa, MariaIron accumulation in the liver in hereditary hemochromatosis (HH) has been shown to be highly variable. Some studies point to the importance of major histocompatibility complex (MHC) class I (MHC-I) and CD8(+) cells as modifiers of iron overload. In this report, using mice knockout for H2K(b-/-) and H2D(b-/-) genes, it is demonstrated that lack of classical MHC-I molecules results in a spontaneous increase of n...
Reposição do sistema semi-automático Pyxis® num Hospital Central Universitário:...
Miranda, Pedro; Pinto, Mónica; Pereira, Rui; Ribeiro, Eduarda; Ferreira, Sónia; Carvalho, António; Carinha, Paulo HortaIntrodução: No Centro Hospitalar de São João, EPE a partir de 2008, foi implementado o sistema semi-automático de reposição de stocks nivelados de medicamentos, Pyxis®, atualmente implementado em 16 serviços clínicos. Atendendo ao crescimento verificado na implementação deste sistema automatizado na instituição, este trabalho pretende dar a conhecer a realidade de preparação da medicação para reposição no siste...