60 documents found, page 1 of 6
Cognitive impairment in prostate cancer patients receiving androgen deprivation...
Barreira, João Vasco; Barreira, Pedro; Falcão, Gil; Garcez, Daniela; Silva, Pedro; Santos, Gustavo; Fontes-Sousa, Mário; Mendes, José Leão; Reis, FilipaBackground: Androgen deprivation therapy (ADT) is a primary treatment for prostate cancer (PCa) that effectively reduces androgen levels to suppress tumor progression. However, growing evidence suggests potential cognitive side effects, raising concerns about the long-term neurological consequences of this treatment. Objective: This scoping review aims to synthesize the existing evidence linking ADT to cognitiv...
Evaluation of inhibitory control and attentional bias through eye-tracking: a m...
Barros, Gonçalo; Ribeiro, FilipaObsessive-compulsive disorder (OCD) is characterized by deficits in inhibitory control and attentional processes. The emotional nature of stimuli can significantly influence these cognitive processes, yet traditional paradigms assessing inhibitory responses, such as the Stop-Signal Task, typically neglect emotional stimuli. This limitation reduces their capacity to capture the cognitive impairments associated w...
The efficacy of virtual reality-based EEG neurofeedback in health-related sympt...
Castanho, Lina; Martinho, Diogo Vicente; Saial, Ana Cristina; Gouveia, Bruna Raquel; Gouveia, Élvio Rúbio; Ribeiro, FilipaEEG Neurofeedback is a noninvasive therapeutic modality that can potentially modify targeted aspects of brain function, considered promising for the treatment of neuropsychiatric disorders. Nevertheless, some limitations have considerable potential to compromise its efficacy, including the requirement for a high number of sessions, the repetition of therapeutic tasks, and the challenge in sustaining the objecti...
Estudo experimental das doses por Tomografia Computorizada de Feixe Cónico em r...
Anastácio Bonito , André Filipe; Cravo Sá, Ana; Ribeiro, Filipa; Campos, Guilherme; Moreno , Lília; Jesus Costa , Maria; Pontes , MiguelEnquadramento: A Tomografia Computorizada por Feixe Cónico (TCFC) é usada para verificação dos tratamentos em radioterapia (RT). Contudo, a sua utilização implica uma dose adicional de radiação para o doente o que poderá potenciar preocupações sobre os efeitos tecidulares a longo prazo [1-4]. Objetivos: Pretende-se, avaliar as doses absorvidas por TCFC nos protocolos de cabeça, tórax e pélvico e entre três inst...
Cleavage of the TrkB-FL receptor during epileptogenesis: insights from a kainic...
Ribeiro Rodrigues, Leonor; Fonseca-Gomes, João; Paulo, Sara L; Viais, Ricardo; Ribeiro, Filipa; Miranda-Lourenço, Catarina; Mouro, FranciscoBrain-derived neurotrophic factor (BDNF) is essential for neuronal survival, differentiation, and plasticity. In epilepsy, BDNF exhibits a dual role, exerting both antiepileptic and pro-epileptic effects. The cleavage of its main receptor, full-length tropomyosin-related kinase B (TrkB-FL), was suggested to occur in status epilepticus (SE) in vitro. Moreover, under excitotoxic conditions, TrkB-FL was found to b...
PD-1 and ICOS are coexpressed in T follicular helper cells but define three sta...
Ribeiro, Filipa; Antunes, Diogo; Pires, Ana R.; Rino, José; Filipe, Beatriz; Jesus, Kátia; Correia, Ricardo; Fonseca, Válter R; Kumar, SaumyaHumoral responses to infection or vaccination require T cell-B cell interactions. T follicular helper (TFH) cells drive germinal center (GC) responses by providing help to B cells, whereas T follicular regulatory (TFR) cells regulate them. Both mature GC-located TFH and TFR cells are widely characterized by the expression of ICOS and PD-1. However, although human TFR cells share many phenotypic characteristics ...
Otimização de formulações de extrusão de zeólitos recorrendo a planeamento fato...
Valle, Lívia; Ferreira, Ricardo; Fernandes, Auguste; Lourenço, João P.; Silva, João M.; João, Isabel M.; Ribeiro, FilipaUm planeamento de experiencias fatorial completo foi utilizado, abrangendo três variáveis independentes em dois níveis, para avaliar os principais parâmetros que influenciam o processo de extrusão. O estudo teve como objetivo otimizar as propriedades do extraído em relação ‡ microporosa ade e ‡ resistência mecânica. As variáveis investigadas incluíram o teor de zeólito (% mássica), a razão ácido/aglomerante (m/...
Biobased routes for the upgrading of α-angelica lactone to value added products
Antunes, Margarida M.; Silva, Andreia F.; Skrodczky, Kai; Fernandes, Auguste; Ribeiro, Filipa; Russo, Patricia A.; Pinna, Nicola; Pillinger, MartynBiomass derived compounds are important building blocks to produce value added bioproducts. These bioproducts can replace fossil fuel derivatives in a more sustainable approach, contributing to reduce CO2 emissions and a circular economy. More attention has been given to angelica lactone compounds due to their potential to be reduced to gamma-valerolactone (GVL) and other biobased products with several importan...
Teleneuropsychology: reliability and acceptance in memory assessment
Varandas, Mariana; Ribeiro, FilipaIntroduction: The use of telehealth in psychological interventions has experienced a significant increase in recent years. This form of patient interaction has important implications, especially in neuropsychological assessment. Given the limited research on this subject in Portugal, the reliability of neuropsychological tests and acceptance of this format by the Portuguese elderly must be studied. Methods: The...
Inclusão na rotina do doseamento da hormona Anti-Mulleriana para avaliação da f...
Ribeiro, Filipa; Lamas, Maria Céu; Farinha, Rui; Gomes, Diana; Mota, Sandra; Amorim, ManuelaA hormona Anti-Mulleriana (AMH) é atualmente conhecida como capaz de traduzir a reserva ovárica e a qualidade dos oócitos. A degradação dos oócitos é bastante comum quando a mulher tem comportamentos de risco que influenciem negativamente a fertilidade, como os hábitos tabágicos. A fertilidade é muito influenciada por este hábito, traduzindo-se numa degradação gradual e exacerbada dos oócitos. Por existir uma i...