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Antimicrobial and wound healing effects associated to cytocompatibility and the...

Machado, Alexandra M.; Marto, Joana; Gonçalves, Lídia Maria; Ribeiro, Helena Margarida; Duarte, Aida; Tomás, Andreia; Falcão, Soraia I.

Owing to its applications in both food and pharmaceutical industries honey is regarded as a functional product. This study evaluated 32 Portuguese monofloral honeys and their activity was compared with manuka honey 850 +. The antimicrobial activity was determined against Gram-positive and negative bacteria, and yeast. Antioxidant activity, wound healing ability, and cell viability were studied in the human kera...


In vitro biological activity and phenolic profile of selected portuguese monofl...

Machado, Alexandra M.; Marto, Joana; Gonçalves, Lídia Maria; Ribeiro, Helena Margarida; Duarte, Aida; Tomás, Andreia; Falcão, Soraia; Vilas-Boas, Miguel

Portuguese monofloral honeys from carob tree, chestnut, bell heather, eucalyptus, incense, orange, and strawberry tree, were evaluated in vitro for antimicrobial, antioxidant, wound healing, and cell viability effect, compared to manuka honey 850+. Antimicrobial activity was determined against Gram+-and Gram- bacteria and yeast. Antioxidants, wound healing, and cell viability effects were studied in the Human K...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Innovative, Sugar-Free Oral Hydrogel as a Co-administrative Vehicle for Pediatr...

Pereira, Margarida; Cosme Silva, Filipa; Simões, Sandra; Ribeiro, Helena Margarida; Almeida, António José; Marto, Joana

Palatability and swallowability in the pediatric population are perceived as true challenges in the oral administration of medication. Pediatric patients have high sensitivity to taste and reduced ability to take solid dosage forms, which can often lead to a poor therapeutic compliance. It is crucial to find new strategies to simplify the oral administration of drugs to children. The present paper reports the d...


Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Pro...

Couto, Joana; Figueirinha, Artur; Batista, Maria Teresa; Paranhos, António; Nunes, Carla; Gonçalves, Lídia Maria; Marto, Joana; Fitas, Manuel

Fragaria vesca L. (F. vesca), popularly known as wild strawberry, is a plant from the Rosaceae family, found in temperate and subtropical areas of the northern hemisphere. F. vesca leaves have been shown to have antiseptic, emollient, and dermatological protection properties, due to the presence of bioactive compounds, such as flavonoids, phenolic acids, ellagitannins, and proanthocyanidins. In this study, a F....


Pickering Emulsions Stabilized by Calcium Carbonate Particles: A New Topical Fo...

Marto, Joana; Nunes, Andreia; Martins, Ana Margarida; Carvalheira, João; Prazeres, Pedro; Gonçalves, Lídia; Marques, Alexandre; Lucas, António

Pickering emulsions are systems composed of two immiscible fluids stabilized by solid organic or inorganic particles. Pickering emulsions are particularly useful in cosmetics, where the surfactants are unwanted, as well as in the pharmaceutical field, where transdermal and/or dermal drug delivery is difficult to achieve and controlled drug release is desired. Here, we studied calcium carbonate particles as stab...


Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Pro...

Couto, Joana; Figueirinha, Artur; Batista, Maria Teresa; Paranhos, António; Nunes, Carla; Gonçalves, Lídia; Marto, Joana; Fitas, Manuel; Pinto, Pedro

Fragaria vesca L. (F. vesca), popularly known as wild strawberry, is a plant from the Rosaceae family, found in temperate and subtropical areas of the northern hemisphere. F. vesca leaves have been shown to have antiseptic, emollient, and dermatological protection properties, due to the presence of bioactive compounds, such as flavonoids, phenolic acids, ellagitannins, and proanthocyanidins. In this study, a F....


Highlighting the biological potential of the brown seaweed Fucus spiralis for s...

Freitas, Rafaela; Martins, Alice; Silva, Joana; Alves, Celso; Pinteus, Susete; Alves, Joana; Teodoro, Fernando; Ribeiro, Helena Margarida

Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matrix, also enhanced by enzymatic degradation of matrix supporting molecules. Thus, and with the growing demand for eco-friendly skin products, natural compounds extracted from brown seaweeds revea...

Date: 2020   |   Origin: IC-online

Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for S...

Freitas, Rafaela; Martins, Alice; Silva, Joana; Alves, Celso; Pinteus, Susete; Alves, Joana; Teodoro, Fernando; Ribeiro, Helena Margarida

Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matrix, also enhanced by enzymatic degradation of matrix supporting molecules. Thus, and with the growing demand for eco-friendly skin products, natural compounds extracted from brown seaweeds revea...


Flavonoid-Enriched Plant-Extract-Loaded Emulsion: A Novel Phytocosmetic Sunscre...

Cefali, Letícia Caramori; Ataide, Janaína Artem; Fernandes, Ana Rita; Sousa, Ilza Maria de Oliveira; Gonçalves, Fernanda Cristina da Silva

The aim of this study was to develop a phytocosmetic sunscreen emulsion with antioxidant effect, containing a blend of flavonoid-enriched plant extracts. In vitro sun protection factor, antioxidant activity, skin irritation, photostability, cutaneous permeation, and retention of flavonoids were evaluated. Thermodynamically stable emulsions were obtained and tested for sensorial analysis after loading the blend ...


In vitro SPF and photostability assays of emulsion containing nanoparticles wit...

Cefali, Letícia Caramori; Ataide, Janaína Artem; Eberlin, Samara; Gonçalves, Fernanda Cristina da Silva; Fernandes, Ana Rita; Marto, Joana

The aim of study was to determine the in vitro sun protection factor (SPF) and the photostability profile of a topical formulation composed of nanoparticles loaded with vegetable extracts and to assess its physicochemical properties. Chitosan/tripolyphosphate (TPP) nanoparticles loaded with flavonoids-enriched vegetable extracts (Ginkgo biloba L., Dimorphandra mollis Benth, Ruta graveolens, and Vitis vinifera L...


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