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An insight into the sialotranscriptome and virome of Amazonian anophelines

Scarpassa, Vera Margarete; Debat, Humberto; Alencar, Ronildo Baiatone; Saraiva, José Ferreira; Calvo, Eric; Arcà, Bruno; Ribeiro, J. M.C.

Background: Saliva of mosquitoes contains anti-platelet, anti-clotting, vasodilatory, anti-complement and anti-inflammatory substances that help the blood feeding process. The salivary polypeptides are at a fast pace of evolution possibly due to their relative lack of structural constraint and possibly also by positive selection on their genes leading to evasion of host immune pressure. Results: In this study, ...

Date: 2020   |   Origin: Oasisbr

The Genome of Anopheles darlingi, the main neotropical malaria vector

Marinotti, Osvaldo; Cerqueira, Gustavo C.; Almeida, Luiz G.P.; Ferro, Maria Inês Tiraboschi; Loreto, Elgion Lúcio da Silva; Zaha, Arnaldo

Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of malaria per year on the American continent. Anopheles darlingi diverged from the African and Asian malaria vectors ∼100 million years ago (mya) and successfully adapted to the New World environment. Here we present an annotated reference A. darlingi genome, sequenced from a wild population of males and f...

Date: 2020   |   Origin: Oasisbr

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