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Reduction of Oximes and Hydrazones: Asymmetric and Diastereoselective Approaches
Ribeiro, João L. P.; Alves, Cláudia; Cardoso, Ana L.; Lopes, Susana M. M.; Pinho e Melo, Teresa M. V. D.The asymmetric reduction of oximes and hydrazones is an attractive and versatile strategy for the synthesis of chiral amines, which are valuable building blocks in organic synthesis. This review summarizes the relevant developments, made in the last decade, on the enantioselective and diastereoselective reduction of oximes and hydrazones involving metal-catalyzed hydrogenation/hydrogenolysis reactions, hydride ...
Date: 2021
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Origin: Estudo Geral - Universidade de Coimbra