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Western outcomes of circumferential endoscopic submucosal dissection for early ...

de Santiago, Enrique Rodríguez; van Tilburg, Laurelle; Deprez, Pierre H.; Pioche, Mathieu; Pouw, Roos E.; Bourke, Michael J.; Seewald, Stefan

Background and Aims: Circumferential endoscopic submucosal dissection (cESD) in the esophagus has been reported to be feasible in small Eastern case series. We assessed the outcomes of cESD in the treatment of early esophageal squamous cell carcinoma (ESCC) in Western countries. Methods: We conducted an international study at 25 referral centers in Europe and Australia using prospective databases. We included a...


X-tackling the path to closure: post-endoscopic submucosal dissection defect re...

Neves, João A. Cunha; Chaves, Jéssica; Ribeiro, Mário Dinis; Libânio, Diogo

Mucosal defect closure after endoscopic submucosal dissection (ESD) may reduce the likelihood of delayed bleeding and perforation [1]. Several devices are currently available for the closure of mucosal defects, including through-the-scope (TTS) and over-the-scope (OTS) clips, and OTS endoscopic suturing devices. However, defect closure can be technically demanding, with TTS clips typically limited to defects up...


Perspectives and awareness of endoscopy healthcare professionals on sustainable...

Neves, João A. Cunha; Santiago, Enrique Rodriguez de; Pohl, Heiko; Lorenzo-Zúñiga, Vicente; Cunha, Miguel F.; Voiosu, Andrei M.; Römmele, Christoph

Background Gastrointestinal (GI) endoscopy is one of healthcare's main contributors to climate change. We aimed to assess healthcare professionals' attitudes and the perceived barriers to implementation of sustainable GI endoscopy. Methods The LEAFGREEN web-based survey was a cross-sectional study conducted by the European Society of Gastrointestinal Endoscopy (ESGE) Green Endoscopy Working Group. The questionn...


Gaining competence in needle - knife fistulotomy - can I begin on my own?

Lopes, Luís; Ribeiro, Mário Dinis; Gonçalves, Carla Rolanda Rocha

BACKGROUND: While there are guidelines for appropriate training in ERCP, these are non-existent for needle-knife precut. The aim of this study was: (1) evaluate the experience curve of three endoscopists in needle-knife fistulotomy (NKF); (2) propose a minimum number of NKF procedures to attest proficiency. METHODS: Between November 1997 and March 2011, the first 120 consecutive NKF performed by three endoscopi...


Simulator training in gastrointestinal endoscopy - from basic training to advan...

Wiel, S. E. van der; Magalhaes, R. Küttner; Gonçalves, Carla Rolanda Rocha; Ribeiro, Mário Dinis; Bruno, M. J.; Koch, A. D.

Simulator-based gastrointestinal endoscopy training has gained acceptance over the last decades and has been extensively studied. Several types of simulators have been validated and it has been demonstrated that the use of simulators in the early training setting accelerates the learning curve in acquiring basic skills. Current GI endoscopy simulators lack the degree of realism that would be necessary to provid...


Lower-limb amputation following foot ulcers in patients with diabetes : classif...

Soares, Matilde Monteiro; Mendes, Daniela Martins; Carneiro, António Vaz; Ribeiro, Mário Dinis

Background: This study aimed to validate and compare the existing systems developed to stratify subjects with diabetic foot ulcers by risk of consequent lower extremity amputation. Methods: We conducted a prospective cohort study on a consecutive series of patients (mean age of 68 years; 64% male) with active ulcer who were attending our Hospital Diabetic Foot Clinic (n = 293) from January 2010 to March 2013. A...


Early precut fistulotomy for biliary access: time to change the paradigm of "th...

Lopes, Luís; Ribeiro, Mário Dinis; Rolanda, Carla

The precut timing during the biliary cannulation algorithm is a subject of controversy. Some studies suggest that early institution of precut is a safe and effective strategy even though the extent to which this approach may affect the duration of the ERCP is seldom addressed. OBJECTIVE: To assess the success, safety, and procedure duration of an early precut fistulotomy (group A) versus a classic precut strate...


Emergencies after endoscopic procedures

Gonçalves, Carla Rolanda Rocha; Caetano, Ana Célia; Ribeiro, Mário Dinis

Endoscopy adverse events (AEs), or complications, are a rising concern on the quality of endoscopic care, given the technical advances and the crescent complexity of therapeutic procedures, over the entire gastrointestinal and bilio-prancreatic tract. In a small percentage, not established, there can be real emergency conditions, as perforation, severe bleeding, embolization or infection. Distinct variables int...


Validation of a fluorescence in situ hybridization method using peptide nucleic...

Cerqueira, L.; Fernandes, R. M.; Ferreira, Rui M.; Oleastro, Mónica; Carneiro, Fátima; Brandão, Catarina; Nunes, Pedro Pimentel; Ribeiro, Mário Dinis

Here, we evaluated a previously established peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) method as a new diagnostic test for Helicobacter pylori clarithromycin resistance detection in paraffin-embedded gastric biopsy specimens. Both a retrospective study and a prospective cohort study were conducted to evaluate the specificity and sensitivity of a PNA-FISH method to determine H. pylori cla...


Probe4pylori: a new kit for the rapid detection of H. pylori and associated cla...

Cerqueira, L.; Fernandes, R. M.; Ferreira, Rui M.; Oleastro, Mónica; Carneiro, Fátima; Brandão, Catarina; Nunes, Pedro Pimentel; Ribeiro, Mário Dinis

In this study an evaluation of Probe4Pylori, a previously established PNA-FISH diagnostic test for H. pylori clarithromycin resistance in paraffin embedded gastric biopsies was performed and compared against culture followed by E-test and PCR. The Probe4Pylori showed very promising results with values of sensitivity (80%) and specificity (approximately 90%) for the patients harboring clarithromycin-resistant H....


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