5 documents found, page 1 of 1
Production of human milk fat substitutes enriched in omega-3 polyunsaturated fa...
Tecelão, Carla; Silva, Joana; Dubreucq, Eric; Ribeiro, Maria H.; Ferreira-Dias, SuzanaIn human milk fat (HMF), palmitic acid (20-30%), the major saturated fatty acid, is mostly esterified at the sn-2 position of triacylglycerols, while unsaturated fatty acids are at the sn-1,3 positions, conversely to that occurring in vegetable oils. This study aims at the production of HMF substitutes by enzyme-catalyzed interesterification of tripalmitin with (i) oleic acid (system I) or (ii) omega-3 polyunsa...
Anti-inflammatory activity of naringin and the biosynthesised naringenin by nar...
Amaro, Maria Ines; Rocha, Joao; Vila-Real, Helder; Eduardo-Figueira, Maria; Mota-Filipe, Helder; Sepodes, Bruno; Ribeiro, Maria H.A great number of antioxidants are naturally present in citrus juice, being responsible for their potentially protective action against inflammation. Naringin, a bitter compound, in citrus, is hydrolysed by naringinase into tasteless naringenin and to rhamnose and glucose. The aim of this study was to evaluate the anti-inflammatory activity of naringin and naringenin in an acute model of induced colitis in mice...
Effect of naringin enzymatic hydrolysis towards naringenin on the anti-inflamma...
Ribeiro, Isabel A.; Rocha, Joao; Sepodes, Bruno; Mota-Filipe, Helder; Ribeiro, Maria H.The aim of this work was the hydrolysis of naringin towards naringenin with immobilized naringinase and the evaluation of their anti-inflammatory activity. An acute local inflammation model (rat paw edema induced by X-carrageenan) was chosen to evaluate the contribution of antioxidant properties to a possible anti-inflammatory effect. Grapefruit juice was processed with naringinase immobilized in k-carrageenan ...
Immobilization of naringinase by selective adsorption and covalent binding to m...
Russo, Joana; Barreiro, Maria Ines; Vila-Real, Helder; Ribeiro, Maria H.
Association of HFE common mutations with Parkinson's disease, Alzheimer's disea...
Guerreiro, Rita J.; Brás, José M.; Santana, Isabel; Januário, Cristina; Santiago, Beatriz; Morgadinho, Ana S.; Ribeiro, Maria H.; Hardy, JohnBackground: Pathological brain iron deposition has been implicated as a source of neurotoxic reactive oxygen species in Alzheimer (AD) and Parkinson diseases (PD). Iron metabolism is associated with the gene hemochromatosis (HFE Human genome nomenclature committee ID:4886), and mutations in HFE are a cause of the iron mismetabolism disease, hemochromatosis. Several reports have tested the association of HFE var...