14 documents found, page 1 of 2

Preliminary data on the ecotoxicity effects of the novel synthetic cathinone 3,...

Background: The use of synthetic cathinones (SC) for recreational purposes has become increasingly common among young individuals in recent years [1]. As a result, SC have been detected in aquatic environments even at low concentrations (between ng L‒1 to µg L‒1) [2] that can negatively impact freshwater vertebrates [3]. Since SC are designed to affect the nervous system, they could potentially cause unpredicta...

Effects on apoptosis and neurotransmitters after exposure to 3-chloromethcathin...

Background: Synthetic cathinones are a class of new psychoactive substances (NPS) widely consumed worldwide. Their large-scale production and constant structural modifications lead to the emergence of new NPS every year. 3-Chloromethcathinone (3-CMC) was first identified on the European market in 2014 and is a halogenated and N-alkylated derivative of cathinone [1]. 3-CMC has a chiral centre, giving rise to two...

Genotoxicidade na minhoca Eisenia fetida exposta a metafedrona e cetamina

A metafedrona e a cetamina são duas substâncias psicoativas (SPAs) utilizadas para fins recreativos e que podem ser detetadas nos ecossistemas terrestres devido à irrigação dos solos com águas contaminadas, aplicação de lamas provenientes de estações de tratamento de águas residuais, entre outros. Apesar de chegarem aos solos, pouco se sabe acerca dos efeitos tóxicos que as SPAs podem induzir nos organismos ter...

Avaliação do efeito tóxico da metafedrona em minhocas da espécie Eisenia fetida...

O aumento do consumo de substâncias psicoativas (SPAs) tem gerado preocupação ambiental, devido ao consequente aumento de SPAs nos ecossistemas de água doce e terrestre. A metafedrona (3-MMC) é uma catinona sintética excretada na urina após o seu consumo, podendo chegar ao ambiente. Devido à presença das SPAs no solo, torna-se importante estudar os efeitos que podem ter nos organismos edáficos. Assim, o objetiv...

Sublethal enantiotoxicity of MDMA on the development, teratogenicity, genotoxic...

Background: Chiral psychoactive substances (PAS) as amphetamine-like substances are among the main group of drugs seized in Europe. The increased attractiveness of these drugs resulted in their widespread occurrence in the environment raising concern about their possible hazardous effects to non-target organisms [1, 2]. PAS metabolism in humans and biodegradation in wastewater treatment plants is stereosel...

Evaluation of oxidative stress and apoptosis responses in zebrafish (Danio reri...

Background: The emergence of new psychoactive substances (NPS) in the worldwide drug market raises huge concerns over public health, drug policy and environmental adverse effects [1]. Butylone (BTL) is a synthetic chiral cathinone [2] reported in wastewater effluents and despite its increasing presence in freshwater ecosystems, no studies were found on the BTL toxic evaluation in fish, including the well-known ...

A POLUIÇÃO DO SOLO: CAUSAS, FONTES E PRINCIPAIS POLUENTES

Soil is an important resource for ecosystems, wildlife and agriculture. Since the industrial revolution, thousands of compounds have been used, produced and released involuntarily or even voluntarily (i.e. pesticides and bombs) into the environment, affecting the soil. Different sources and different types of pollutants will affect soil fauna, aquatic ecosystems and food chains. These compounds can bioaccumulat...

Efeito da cetamina na fauna edáfica: ensaios de fuga e reprodução com Eisenia f...

A utilização crescente de cetamina para fins terapêuticos e recreativos tem motivado preocupações ao nível ambiental. Esta substância tem sido detetada em efluentes, devido à ineficiência das técnicas aplicadas nas estações de tratamento de águas residuais. Sendo que parte destes efluentes podem ser usados como águas para reutilização em práticas agrícolas, importa perceber os efeitos que a cetamina apresenta e...

Enantioselective ecotoxicity of venlafaxine in aquatic organisms: Daphnia and z...

Venlafaxine is a chiral antidepressant detected in aquatic compartments. It was recently included in the 3rd Watch List from the European Union. The present study aimed to investigate venlafaxine toxicity effects, targeting possible enantioselective effects, using two aquatic organisms, daphnia (Daphnia magna) and zebrafish (Danio rerio). Specimens were exposed to both racemate, (R,S)-venlafaxine (VEN), and to ...

Eisenia Fetida – preliminary data