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Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review wi...

Ribeiro, Paulo Renato; Ferreira, Carmen; Antunes, Carlos; Dias, Gonçalo; Cunha Silva Reis Lima, Maria Joao; de Pinho Ferreira Guiné, Raquel

Background: Neurodegenerative diseases, including spastic paraplegia type 11 (SPG11), are complex disorders characterized by progressive neurological decline and significant metabolic disturbances. Spatacsin, the protein encoded by the SPG11 gene, plays a critical role in autophagy and lysosomal homeostasis, which are essential for neuronal health. Its impairment leads to defective cellular clearance and neurod...

Date: 2025   |   Origin: Repositório Científico do Instituto Politécnico de Viseu
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