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Effect of sodium alendronate on alveolar bone resorption in experimental period...

Menezes, Adriana Magalhães Andrade de.; Rocha, Francisco Airton C.; Chaves, Hellíada V.; Carvalho, Cibele Barreto Mano de; Ribeiro, Ronaldo Albuquqerque

Background: Bisphosphonates are potent inhibitors of bone resorption and were shown to inhibit bone resorption in experi- mental periodontitis by unknown mechanisms. We studied the effect of the aminobisphosphonate sodium alendronate (SA) in experimental periodontitis. Wistar rats were subjected to liga- ture placement around the second upper left molars. Methods: Animals were treated with SA 0.01 to 0.25 mg/kg...

Date: 2013   |   Origin: Oasisbr
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