15 documents found, page 1 of 2
RP-13 Professional year at FMUL: students and residents' perceived autonomy in ...
Cabete, Sara; Ribeiro, Ruy; Patrício, MadalenaIntroduction and Goal Medical schools through their curricula play a major role in the success of the newly graduated doctors, being socially responsible for offering the best opportunities for students to develop the knowledge, skills and attitudes expected from a highly professional doctor. At FMUL, the sixth- final-year is a professional year with well-defined transversal and specific competences to be acqui...
Association of the practice of contact sports with the development of amyotroph...
Henriques, Ana; Gromicho, Marta; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Petri, Susanne; Uysal, Hilmi; Pinto, Susana; Antunes, MariliaObjectives: High-intensity physical activity and sports prone to repetitive injuries of the cervical spine and head (when associated with vigorous practice) have been suggested as possible risk factors for amyotrophic lateral sclerosis (ALS). Our objective was to evaluate the relationship between the practice of contact sports (boxing, hockey, football, rugby) and ALS. Methods: The study included 2247 individua...
Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months
Malato, João; Ribeiro, Ruy; Fernandes, Eugénia; Leite, Pedro Pinto; Casaca, Pedro; Antunes, Carlos; Fonseca, Valter R; Gomes, MC; Graca, LuisThe coverage of SARS-CoV-2 vaccination in large parts of the world, together with the high number of breakthrough infections, especially following the emergence of Omicron subvariants, makes hybrid immunity (resulting from vaccine and infection) common. Hybrid immunity, particularly after BA.1 or BA.2 infection, confers substantial protection against the BA.5 infection. However, although the waning of protectio...
The percentage of −2 pro–prostate-specific antigen and the prostate health inde...
Garrido, Manuel Matos; Marta, José C.; Bernardino, Rui M.; Guerra, João; Fernandes, Francisco; Pereira, Maria H.; Ribeiro, Ruy; Holdenrieder, StefanContext.—: There is a need to avoid the overdiagnosis of prostate cancer (PCa) and to find more specific biomarkers. Objective.—: To evaluate the clinical utility of [-2]pro-prostate-specific antigen ([-2]proPSA) derivatives in detecting clinically significant PCa (csPCa) and to compare it with prostate-specific antigen (PSA) and with the percentage of free PSA (%fPSA). Design.—: Two hundred thirty-seven men (P...
Zika virus dynamics : effects of inoculum dose, the innate immune response and ...
Best, Katharine; Barouch, Dan H.; Guedj, Jeremie; Ribeiro, Ruy; Perelson, Alan S.Experimental Zika virus infection in non-human primates results in acute viral load dynamics that can be well-described by mathematical models. The inoculum dose that would be received in a natural infection setting is likely lower than the experimental infections and how this difference affects the viral dynamics and immune response is unclear. Here we study a dataset of experimental infection of non-human pri...
Infective endocarditis as the cause of death: a population-based study in Portu...
Santos de Sousa, Catarina Isabel; Ribeiro, Ruy; Pinto, Fausto J.Introduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends. Material and methods: Retrospective cohort study of all patients whose main cause of death was Infective en...
Are proinflammatory cytokines relevant for the diagnosis of prostate cancer?
Garrido, Manuel Matos; Ribeiro, Ruy; Krüger, Kimberly; Pinheiro, Luís C.; Guimarães, João T.; Holdenrieder, StefanBackground/aim: Inflammation plays an important role in prostate cancer (PCa). We evaluated proinflammatory cytokines regarding differential diagnosis of PCa in men with PSA levels between 2-10 ng/ml. Patients and methods: Serum samples of 79 men (PSA 2-10 ng/ml) were analyzed for 10 proinflammatory cytokines (IL-6, IL-8, TNF-α, IFN-γ, IL-10, IL-1β, IL-2, IL-4, IL-12p70, IL-13) and results were evaluated regard...
The prostate health index (PHI) density : are there advantages over PHI or over...
Garrido, Manuel Matos; Ribeiro, Ruy; Pinheiro, Luís C.; Holdenrieder, Stefan; Guimarães, João T.Background and aims: Overdiagnosis of prostate cancer (PCa) should be minimized. We wanted to evaluate the diagnostic performance of the prostate health index density (PHID) and compare it with that of the prostate health index (PHI) alone and of the prostate-specific antigen density (PSAD). Materials and methods: 232 men scheduled for a prostate biopsy (prostate-specific antigen level: 2-10 µg/L), were enrolle...
Telemonitoring of daily activities compared to the six-minute walk test further...
Santos, Catarina; Santos, Ana Filipe; das Neves, Rui César; Ribeiro, Ruy; Rodrigues, Fatima; Caneiras, Catia; Spruit, Martijn A.; Bárbara, CristinaPulmonary rehabilitation is based on a thorough patient assessment, including peripheral oxygen saturation (SpO2) and heart rate (HR) at rest and on exertion. To understand whether exercise-field tests identify patients who desaturate (SpO2 < 90%) during physical activities, this study compared the six-minute walk test (6MWT) and daily-life telemonitoring. Cross-sectional study including 100 patients referred f...
The burden of infective endocarditis in Portugal in the last 30 years : a syste...
Santos De Sousa, Catarina Isabel; Ribeiro, Ruy; Pinto, Fausto J.Introduction: Infective endocarditis affects cardiac valves or devices and has a potentially uncertain prognosis. Little information is available on the epidemiology of this disease in Portugal. Objective: A systematic review of all evidence published in the last 30 years to assess epidemiological data in patients hospitalized with infective endocarditis in Portuguese hospital centers. Methods: Extensive search...