35 documents found, page 1 of 4
Interplay between liver and blood stages of Plasmodium infection dictates malar...
Chora, Ângelo Ferreira; Marques, Sofia; Lisboa Gonçalves, Joana; Lima, Priscila; Gomes Da Costa, Daniel; Fernandez-Ruiz, Daniel; Marreiros, Maria InêsPlasmodium replicates within the liver prior to reaching the bloodstream and infecting red blood cells. Because clinical manifestations of malaria only arise during the blood stage of infection, a perception exists that liver infection does not impact disease pathology. By developing a murine model where the liver and blood stages of infection are uncoupled, we showed that the integration of signals from both s...
Infective Endocarditis as the Cause of Death: A Population based Study in Portu...
de Sousa, Catarina; Ribeiro, Ruy M.; Pinto, Fausto J.Introduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends.Material and Methods: Retrospective cohort study of all patients whose main cause of death was Infective end...
The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from ...
Nogueira, Paulo Jorge; de Araújo Nobre, Miguel; Costa, Andreia; Ribeiro, Ruy M.; Furtado, Cristina; Bacelar Nicolau, Leonor; Camarinha, CatarinaBackground: It is essential to study the effect of potential co-factors on the risk of death in patients infected by COVID-19. The identification of risk factors is important to allow more efficient public health and health services strategic interventions with a significant impact on deaths by COVID-19. This study aimed to identify factors associated with COVID-19 deaths in Portugal. Methods: A national datase...
Reply to comment on Nogueira, P.J., et al. “the role of health preconditions on...
Nogueira, Paulo Jorge; Nobre, Miguel de Araújo; Costa, Andreia; Ribeiro, Ruy M.; Furtado, Cristina; Nicolau, Leonor Bacelar; Camarinha, Catarina
The role of health preconditions on COVID-19 deaths in Portugal: evidence from ...
Nogueira, Paulo Jorge; Nobre, Miguel de Araújo; Costa, Andreia; Ribeiro, Ruy M.; Furtado, Cristina; Nicolau, Leonor Bacelar; Camarinha, CatarinaBackground: It is essential to study the effect of potential co-factors on the risk of death in patients infected by COVID-19. The identification of risk factors is important to allow more efficient public health and health services strategic interventions with a significant impact on deaths by COVID-19. This study aimed to identify factors associated with COVID-19 deaths in Portugal. Methods: A national datase...
The role of health preconditions on COVID-19 deaths in Portugal : evidence from...
Nogueira, Paulo Jorge; Nobre, Miguel de Araújo; Costa, Andreia; Ribeiro, Ruy M.; Furtado, Cristina; Bacelar-Nicolau, Leonor; Camarinha, CatarinaBackground: It is essential to study the effect of potential co-factors on the risk of death in patients infected by COVID-19. The identification of risk factors is important to allow more efficient public health and health services strategic interventions with a significant impact on deaths by COVID-19. This study aimed to identify factors associated with COVID-19 deaths in Portugal. Methods: A national datase...
Low doses of ionizing radiation activate endothelial cells and induce angiogene...
Gil Marques, Filipa; Poli, Maria Esmeralda; Malaquias, João; Carvalho, Tânia; Portêlo, Ana; Ramires, Afonso; Aldeia, Fernando; Ribeiro, Ruy M.Purpose: During radiotherapy the peritumoral tissues are daily exposed to subtherapeutic doses of ionizing radiation. Herein, the biological and molecular effects of doses lower than 0.8 Gy per fraction (LDIR), previously described as angiogenesis inducers, were assessed in human peritumoral tissues. Material and methods: Paired biopsies of preperitoneal adipose tissue were surgically collected from 16 patients...
Untangling the immune basis of disease susceptibility
Ribeiro, Ruy M.; Graca, LuisInteractions between immune cell receptors and proteins that determine disease susceptibility shed light on how different arms of the immune system are involved in three viral infections and Crohn's disease.
Novel input for designing patient-tailored pulmonary rehabilitation : telemonit...
Santos, Catarina; César Das Neves, Rui; Ribeiro, Ruy M.; Caneiras, Catia; Rodrigues, Fatima; Spruit, Martijn A.; Bárbara, CristinaPhysical inactivity may be a consequence of chronic diseases but also a potential modifiable risk factor. Therefore, it should be clinically assessed as a vital sign of patients’ general physical condition prior to any exercise-based intervention. This cross-sectional study describes physical activity in the daily life of 100 chronic respiratory patients before pulmonary rehabilitation, comparing subjective and...
The impact of negative lymph nodes in the survival outcomes of pN+ patients fol...
Costa, Paulo M.; Lages, Patrícia; Onofre, Susana; Ribeiro, Ruy M.The impact of negative lymph nodes (LNs) on survival of pN+ patients has been recognized. The weight of negative LNs in an inverse lymph node ratio (nR) should be related to its prognostic impact. Five hundred and two consecutive gastric cancer patients, who underwent radical gastrectomy, were included. Patients were split into groups according to the number of harvested nodes and a cross-tabulation with pTNM s...