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Biodegradable films with polysaccharides, proteins, and bioactive compounds fro...

Martins, Valter F. R.; Lopes, Ana I.; Machado, Manuela; Costa, Eduardo M.; Ribeiro, Tânia B.; Poças, Fátima; Pintado, Manuela; Morais, Rui M. S. C.

Microalgae are a sustainable source of bioactive compounds and nutrients that do not compete with crops for arable land. Lobosphaera sp. was used to produce biodegradable films. Bioactive compounds, polysaccharides, and proteins were extracted from this microalga. The total phenolic content (TPC) and antioxidant activity (ABTS, DPPH, and ORAC) of the bioactive-rich extract were determined, and its composition w...


Identification of novel metabolic signatures on human gut microbiota: ellagic a...

Pais, Adriana C. S.; Ribeiro, Tânia B.; Coscueta, Ezequiel R.; Pintado, Maria Manuela; Silvestre, Armando J. D.; Santos, Sónia A. O.

Phenolic compounds are widely known for their beneficial effects on human health. However, it is essential to understand which low molecular weight metabolites are produced by the gut microbiota, when non-absorbed compounds reach the colon, and whether these metabolites are more biologically active than their precursors. In this context, this study aims to explore the gut microbiota metabolites of relevant phen...


Phenolic compounds as modulators of gut microbiota composition: an in vitro bat...

Pais, Adriana C. S.; Ribeiro, Tânia B.; Coscueta, Ezequiel R.; Salsinha, Ana Sofia; Pintado, Maria Manuela; Silvestre, Armando J.D.; Santos, Sónia A. O.

The human diet comprises a variety of bioactive compounds, such as phenolic compounds which are widely present in vegetables and fruits that confer numerous health benefits.1 However, the health benefits of these compounds appear to be directly influenced by a number of factors, including their bidirectional relationship with gut microbiota,1,2 as these compounds are metabolized by these microorganisms, and, si...


Unlocking potential: byproduct extracts for sustainable leather tanning

Silva, Sara; Silva, Isa; Ribeiro, Tânia B.; Pintado, Manuela

Introduction: The urgent need for sustainable leather tanning arises from the deep-rooted environmental and ethical challenges posed by traditional methods, particularly the harmful chrome-based processes. As society becomes increasingly more aware of these challenges, there emerges a growing demand for eco-conscious alternatives, such as vegetable tanning, which harnesses the richness of tannin extracts from p...


Comparison among different green extraction methods of polyphenolic compounds f...

Martins, Valter F. R.; Ribeiro, Tânia B.; Lopes, Ana I.; Pintado, Manuela E.; Morais, Rui M. S. C.; Morais, Alcina M. M. B.

The use of by-products as a source of bioactive compounds with economic added value is one of the objectives of a circular economy. The olive oil industry is a source of olive pomace as a by-product. The olive pomace used in the present study was the exhausted olive pomace, which is the by-product generated from the air drying and subsequent hexane extraction of residual oil from the olive pomace. The objective...


Exploring grain silo residues as lignocellulosic biomass source for sustainable...

Silva, Isa; Ribeiro, Tânia B.; Silva, Sara; Pintado, Manuela

Introduction: Over the years, the replacement of plastic-based materials has become crucial in alleviating the environmental footprint of various industries.1 The footwear industry currently relies on certain petrol- derived materials such as glues, rubbers, and leather, which demand more sustainable alternatives.2 Lignocellulosic matrices (cellulose, hemicellulose, and lignin) are known to be good filling agen...


Gut microbiota modulation induced by pure phenolic compounds: an in vitro fecal...

Pais, Adriana C. S.; Ribeiro, Tânia B.; Coscueta, Ezequiel R.; Salsinha, Ana Sofia; Pintado, Maria Manuela; Silvestre, Armando J. D.


Screening of mediterranean agro-food by-product powders as potential reinforcin...

Ribeiro, Tânia B.; Silva, Isa; Silva, Sara; Pintado, Manuela

Aim: Plastic materials contribute 4.5% to global greenhouse gas (GHG) emissions. The footwear industry contributes significantly to these emissions due to the high plastic use (38-71%) in shoe components. With the aim of reducing the footwear industry's environmental footprint, this study investigated the potential to produce and assess the potential of agro-food by-products (olive pomace (OP), grape stem (GP),...


Metabolism of phenolic compounds by human gut microbiota: insights from in vitr...

Pais, Adriana C. S.; Ribeiro, Tânia B.; Coscueta, Ezequiel R.; Pintado, Maria M.; Silvestre, Armando J. D.; Santos, Sónia A. O.


Unlocking the full potential of green propolis: a novel extraction approach usi...

Contieri, Letícia S.; Ribeiro, Tânia B.; Sosa, Filipe H. B.; Vaz, Bárbara M. C.; Pizani, Rodrigo S.; Pintado, Manuela; Ventura, Sónia P. M.

Propolis is highly diverse and has various health benefits for humans. However, standardizing propolis-based products for use in the pharmaceutical and food industries is challenging. Efficient extraction processes are essential to maximize their biological potential. Ethanol is commonly used as a solvent but has several drawbacks, such as residual flavor and limitations for some individuals. Water is an altern...


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